Results 101 to 110 of about 8,365 (192)
Journal of Biophotonics, Volume 19, Issue 3, March 2026.Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa +3 more
wiley +1 more source
Peptide 1018 bound to ppGpp in vitro and led to degradation of (p)ppGpp in vivo.
, 2014 (A) Binding of peptide 1018 to various nucleotides based on co-precipitation. Peptide 1018 (0.25 mM) was separately mixed with increasing amounts of ppGpp, GTP, ATP, GDP and ADP in buffer (50 mM Tris, pH 7.4) and the extent of co-precipitation was ...
César de la Fuente-Núñez (567571) +4 more
core +1 more source
Bacteriophage Therapy: Current Strategies and Future Perspectives
MedComm, Volume 7, Issue 3, March 2026.This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou +7 more
wiley +1 more source
Phosphotransferase-dependent accumulation of (p)ppGpp in response to glutamine deprivation in Caulobacter crescentus [PDF]
, 2016 The alarmone (p)ppGpp is commonly used by bacteria to quickly respond to nutrient starvation. Although (p)ppGpp synthetases such as SpoT have been extensively studied, little is known about the molecular mechanisms stimulating alarmone synthesis upon ...
De Bolle, Xavier; id_orcid +3 more
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, 2021 The amount of ppGpp was measured relative to total amount of G (pppGpp + ppGpp + GTP) by TLC in MG1655 and ΔrelA strains grown in MOPS media with 0.2% glucose or 0.4% glycerol. Error bars represent SD of two biological replicates.
Chunghwan Ro (11614177) +2 more
core +1 more source
Small, Volume 22, Issue 16, 17 March 2026.Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
Cell cycle control and environmental response by second messengers in Caulobacter crescentus
BMC Bioinformatics, 2020 Background Second messengers, c-di-GMP and (p)ppGpp, are vital regulatory molecules in bacteria, influencing cellular processes such as biofilm formation, transcription, virulence, quorum sensing, and proliferation.
Chunrui Xu +3 more
doaj +1 more source
Nanozymes Integrated Biochips Toward Smart Detection System
Advanced Science, Volume 13, Issue 11, 23 February 2026.This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen +10 more
wiley +1 more source
Epitranscriptomics as a Candidate Universal Modulator of Dormancy Transitions
Ecology and Evolution, Volume 16, Issue 2, February 2026.Dormancy is presented as a conserved, reversible survival program in which epitranscriptomic RNA modifications are proposed to provide a rapid, energy‐efficient layer that establishes, maintains, and terminates the state by modulating mRNA stability, translation, and localization.
Ehsan Pashay Ahi
wiley +1 more source
The Study of a Novel (p)ppGpp Synthase (YwaC) from Bacillus subtilis 168
, 2008 Adaptation to any undesirable change in the environment helps to ensure the survival of many microorganisms. During nutrient starvation, bacteria undergo a stringent response characterized by the accumulation of the alarmone (p)ppGpp.
Dalgleish, Heather
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