Results 111 to 120 of about 18,483,123 (229)
Regulation of (p)ppGpp hydrolysis by a conserved archetypal regulatory domain [PDF]
Nucleic Acids Research, 2018 Sensory and regulatory domains allow bacteria to adequately respond to environmental changes. The regulatory ACT (Aspartokinase, Chorismate mutase and TyrA) domains are mainly found in metabolic-related proteins as well as in long (p)ppGpp synthetase/hydrolase enzymes.
Séverin Ronneau +5 more
openaire +4 more sources
Environmental Microbiology, Volume 27, Issue 11, November 2025.Antibiotic persister cells in Acinetobacter baumannii: review of the molecular mechanisms involved in this physiology, such as toxin/antitoxin, second messengers, SOS response, PAA or membranes; and elimination strategies such as antibiotics or phages.
Delphine Vergoz +3 more
wiley +1 more source
Bacterial Chromosome Replication and DNA Repair During the Stringent Response
Frontiers in Microbiology, 2020 The stringent response regulates bacterial growth rate and is important for cell survival under changing environmental conditions. The effect of the stringent response is pleiotropic, affecting almost all biological processes in the cell including ...
Anurag Kumar Sinha +2 more
doaj +1 more source
Control of Nucleotide Metabolism and Ribosomal Ribonucleic Acid Synthesis During Nitrogen Starvation of \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]
, 1972 Ribosomal ribonucleic acid (RNA) synthesis and ribonucleoside triphosphate metabolism were studied in cultures of Escherichia coli subjected to starvation for inorganic nitrogen.
Irr, Joseph D.
core +1 more source
Metabolic Origin, Role and Fate of the Denaturant Guanidine
Microbial Biotechnology, Volume 18, Issue 11, November 2025.The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin +3 more
wiley +1 more source
Structural and Mechanistic Analysis of (p)ppGpp Synthetases
, 2017 Eines der herausragenden Merkmale von Mikroorganismen ist ihre Fähigkeit, unter einer Vielzahl und sich schnell ändernden Umweltbedingungen zu überleben. Diese Eigenschaft erlaubt es ihnen eine Vielzahl von verschiedensten Habitaten unseres Planeten zu besiedeln.
Steinchen, Wieland +1 more
openaire +2 more sources
(p)ppGpp synthetases regulate the pathogenesis of zoonotic Streptococcus suis
Microbiological Research, 2016 (p)ppGpp-mediated stringent response is one of the main adaption mechanism in bacteria, and the ability to adapt to environment is linked to the pathogenesis of bacterial pathogens. In the zoonotic pathogen Streptococcus suis, there are two (p)ppGpp synthetases, RelA and RelQ.
Jiawen, Zhu +8 more
openaire +2 more sources
Global Regulation by (p)ppGpp and CodY inStreptococcus mutans [PDF]
Journal of Bacteriology, 2008 ABSTRACTThe RelA, RelP, and RelQ enzymes are responsible for the production of the alarmone (p)ppGpp inStreptococcus mutans. A strain lacking all three synthetases (ΔrelAPQ) does not grow in minimal medium lacking the branched-chain amino acids (BCAA) leucine or valine but grows well if isoleucine is also omitted.
José A, Lemos +4 more
openaire +2 more sources
mLife, Volume 4, Issue 5, Page 551-566, October 2025.Abstract Indole‐3‐acetic acid (IAA) is an important plant hormone that regulates a variety of physiological processes in plants, and it is also produced by some microbes. However, the biosynthesis and roles of IAA in microorganisms, particularly in plant pathogens, remain to be determined.
Sinan Li +5 more
wiley +1 more source
Frontiers in Microbiology, 2020 Stringent response mediated by modified guanosine nucleotides is conserved across bacteria and is regulated through the Rel/Spo functions. In Escherichia coli, RelA and SpoT proteins synthesize the modified nucleotides ppGpp and pppGpp, together referred
Rajeshree Sanyal +2 more
doaj +1 more source