Results 81 to 90 of about 18,483,123 (229)
BMC Microbiology, 2010 Background The global ppGpp-mediated stringent response in pathogenic bacteria plays an important role in the pathogenesis of bacterial infections. In Salmonella enterica serovar Typhimurium (S. Typhimurium), several genes, including virulence genes, are
Kumagai Yoshinori +10 more
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BMC Genomics, 2020 Background Pseudomonas syringae is an important plant pathogen, which could adapt many different environmental conditions. Under the nutrient-limited and other stress conditions, P.
Jun Liu +6 more
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The two PPX-GppA homologues from Mycobacterium tuberculosis have distinct biochemical activities [PDF]
, 2012 Inorganic polyphosphate (poly-P), guanosine pentaphosphate (pppGpp) and guanosine tetraphosphate (ppGpp) are ubiquitous in bacteria. These molecules play a variety of important physiological roles associated with stress resistance, persistence, and ...
Chen, Wy +7 more
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mBio, 2021 During nutrient limitation, bacteria produce the alarmones (p)ppGpp as effectors of a stress signaling network termed the stringent response. RsgA, RbgA, Era, and HflX are four ribosome-associated GTPases (RA-GTPases) that bind to (p)ppGpp in ...
Daniel J. Bennison +5 more
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Structural and Functional Analysis of BipA, a Regulator of Virulence in Enteropathogenic Escherichia coli. [PDF]
, 2015 The translational GTPase BipA regulates the expression of virulence and pathogenicity factors in several eubacteria. BipA-dependent expression of virulence factors occurs under starvation conditions, such as encountered during infection of a host.
Blaha, Gregor +4 more
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A (p)ppGpp-Null Mutant of Haemophilus ducreyi Is Partially Attenuated in Humans Due to Multiple Conflicting Phenotypes [PDF]
, 2014 (p)ppGpp responds to nutrient limitation through a global change in gene regulation patterns to increase survival. The stringent response has been implicated in the virulence of several pathogenic bacterial species.
Ellinger, Sheila +8 more
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Role of (p)ppGpp in Biofilm Formation by Enterococcus faecalis [PDF]
Applied and Environmental Microbiology, 2012 ABSTRACT Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient Δ relA , Δ relQ , and Δ relA Δ relQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and ...
Chavez de Paz, Luis E. +3 more
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Polyphosphate granule biogenesis is temporally and functionally tied to cell cycle exit during starvation in Pseudomonas aeruginosa [PDF]
, 2017 Polyphosphate (polyP) granule biogenesis is an ancient and ubiquitous starvation response in bacteria. Although the ability to make polyP is important for survival during quiescence and resistance to diverse environmental stresses, granule genesis is ...
Dieterle, Michael G. +5 more
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Calcium-activated (p)ppGpp Synthetase in Chloroplasts of Land Plants [PDF]
Journal of Biological Chemistry, 2007 The genetic system of chloroplasts, including the machinery for transcription, translation, and DNA replication, exhibits substantial similarity to that of eubacteria. Chloroplasts are also thought to possess a system for generating guanosine 5'-triphosphate ((p)ppGpp), which triggers the stringent response in eubacteria, with genes encoding ...
Tozawa, Y. +6 more
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Pathogens, 2020 Brucella abortus is a pathogenic bacterium able to proliferate inside host cells. During the first steps of its trafficking, it is able to block the progression of its cell cycle, remaining at the G1 stage for several hours, before it reaches its ...
Mathilde Van der Henst +2 more
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