Results 101 to 110 of about 34,114,677 (275)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Second-Generation P-Values, Shrinkage, and Regularized Models
Frontiers in Ecology and Evolution, 2019 Second-generation p-values (SGPVs) are a novel and intuitive extension of classical p-values that better summarize the degree to which data support scientific hypotheses.
Thomas G. Stewart, Jeffrey D. Blume
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Journal of Applied Hematology, 2014 P -value has been criticized because it is widely misunderstood and don′t tell the researchers what they want to know. Many clinical researches mistaken the conclusion of a significant P-value and may be exaggerate small and unimportant difference.
Areej Abdul Ghani Al Fattani
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
P-value summary for comparison of singleplex and multiplex quantification.
, 2016 P-value summary for comparison of singleplex and multiplex quantification.
Walter J. Schulz-Schaeffer (353857) +6 more
core +1 more source
Croatian Journal of Food Science and Technology, 2019 The broken fractions of rice cultivars improved for yield, grain quality, amylose content and tolerance to common production constraints consisting of FARO 44, FARO 52, NERICA L-34, NERICA L-19 and LOCAL RICE. The rice cultivars, Sorghum malt and soybean
MAMUDU HALIDU BADAU +3 more
doaj +1 more source
BMC Medical Research Methodology, 2010 Background: P values are the most commonly used tool to measure evidence against a hypothesis. Several attempts have been made to transform P values to minimum Bayes factors and minimum posterior probabilities of the hypothesis under consideration.
openaire +5 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Annals of Geophysics, 2016 Present study describes the statistical properties of aftershock sequences related with two major Nepal earthquakes (April 25, 2015, MW 7.8, and May 12, 2015, MW 7.2) and their correlations with the tectonics of Nepal Himalaya.
Prasanta Chingtham +3 more
doaj +1 more source