Results 121 to 130 of about 34,114,677 (275)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Confidence with confidence intervals
Indian Journal of Ophthalmology, 1997 When considering the results of a study that reports one treatment to be better than another, what the practicing ophthalmologist really wants to know is the magnitude of the difference between treatment groups. If this difference is large enough, we may
Thomas Ravi +3 more
doaj
Advanced ScienceDespite advancements in therapeutic agents for diabetic chronic wounds, challenges such as suboptimal bioavailability, intricate disease milieus, and inadequate delivery efficacy have impeded treatment outcomes.
Lanlan Zong +9 more
doaj +1 more source
P-values, p-values everywhere! [PDF]
New Zealand Veterinary Journal, 2017 Siva, Ganesh, Vanessa, Cave
openaire +2 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Are realized volatility models good candidates for alternative Value at Risk prediction strategies? [PDF]
In this paper, we assess the Value at Risk (VaR) prediction accuracy and efficiency of six ARCH-type models, six realized volatility models and two GARCH models augmented with realized volatility regressors.
Refenes, Apostolos P. +2 more
core
, 2012 By using critical point theory, we establish the existence of infinitely many weak solutions for a class of elliptic Navier boundary value problems depending on two parameters and involving the p-biharmonic operator. © 2012 Elsevier Ltd.
Livrea, R., Candito, P., Li, L.
core +1 more source
Revista Colombiana de Cirugía, 2005 La evaluación del beneficio de una terapia es crucial para decidir si un nuevo tratamiento debe ser usado. Los clínicos que utilizan los resultados de los experimentos clínicos para guiar su práctica médica necesitan herramientas útiles para evaluar la ...
Eduardo Torregroza-Diazgranados
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source