Results 141 to 150 of about 5,551,414 (241)

Combined P-Value Functions for Compatible Effect Estimation and Hypothesis Testing in Drug Regulation. [PDF]

Stat Med
Pawel S, Roos M, Held L.
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gray Matter Volume Abnormalities in Schizophrenia: Comparisons Between P-Value and Effect Size Inference Frameworks Using Mega- and Meta-Analyses. [PDF]

Schizophr Bull
Li X, Zhu W, Zhao Z, Xie Y, Ding H, Lin L, Du X, Wei X, Zhang Y, Wei L, Ji Y, Chang Z, Ren J, Liu L, Zhang X, Wang L, Tian H, Wang X, Liu W, Lin X, Zhang C, Wang G, Zhang B, Yu C, Qin W.   +24 more
europepmc   +1 more source

The P value - and its historical underpinnings - pro and con. [PDF]

Saudi J Anaesth, 2023
Grech V, Eldawlatly AA.
europepmc   +1 more source

Misinterpreting the p value [PDF]

Anaesthesia, 2017
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The <i>P</i> Value: What It Is and What It Is Not. [PDF]

J Korean Med Sci
Habibzadeh F.
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Decision Rules in Frequentist and Bayesian Hypothesis Testing: P-Value and Bayes Factor. [PDF]

Int J Public Health
Fordellone M, Schiattarella P, Nicolao G, Signoriello S, Chiodini P.   +4 more
europepmc   +1 more source

p value variability and subgroup testing. [PDF]

Eur J Nutr, 2021
Horgan G.
europepmc   +1 more source