Results 11 to 20 of about 41,121 (277)
PacBio Sequencing and Its Applications
Genomics, Proteomics & Bioinformatics, 2015 Single-molecule, real-time sequencing developed by Pacific BioSciences offers longer read lengths than the second-generation sequencing (SGS) technologies, making it well-suited for unsolved problems in genome, transcriptome, and epigenetics research ...
Anthony Rhoads, Kin Fai Au
doaj +5 more sources
Reconstruction of influenza a virus variants from PacBio reads [PDF]
2014 IEEE 4th International Conference on Computational Advances in Bio and Medical Sciences (ICCABS), 2014 © 2014 IEEE. Pacific Biosciences (PacBio) sequencing is providing thousands of reads with the length up to 10,000 bases. In most cases this length is enough to cover entire region of interest however this technology has high (≈ 15%) error rate.
Nicholas C. Wu +11 more
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PaSS: a sequencing simulator for PacBio sequencing [PDF]
BMC Bioinformatics, 2019 Background Third-generation sequencing platforms, such as PacBio sequencing, have been developed rapidly in recent years. PacBio sequencing generates much longer reads than the second-generation sequencing (or the next generation sequencing, NGS ...
Wenmin Zhang, Ben Jia, Chaochun Wei
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2SNV: Quasispecies reconstruction from PacBio reads
2015 IEEE 5th International Conference on Computational Advances in Bio and Medical Sciences (ICCABS), 2015 © 2015 IEEE. Pacific Biosciences (PacBio) sequencing is providing thousands of reads with the length up to 10,000 bases. In most cases this length is enough to cover entire region of interest however this technology has high (≈15%) error rate. We propose
Nicholas C. Wu +11 more
core +3 more sources
Bi-Level Error Correction for PacBio Long Reads [PDF]
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2020 The latest sequencing technologies such as the Pacific Biosciences (PacBio) and Oxford Nanopore machines can generate long reads at the length of thousands of nucleic bases which is much longer than the reads at the length of hundreds generated by Illumina machines. However, these long reads are prone to much higher error rates, for example 15%, making
Yuansheng Liu +3 more
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, 2022 Scripts for analyzing sequence data from 14 PacBio long-read shotgun metagenomes and matching short-read Illumina metagenomes generated from marine water column ...
Nastassia Patin (9109532)
core +1 more source
“polishCLR: a Nextflow workflow for polishing PacBio CLR genome assemblies” [PDF]
Genome Biology and Evolution, 2022 Abstract Long-read sequencing has revolutionized genome assembly, yielding highly contiguous, chromosome-level contigs. However, assemblies from some third generation long read technologies, such as Pacific Biosciences (PacBio) Continuous Long Reads (CLR), have a high error rate.
Jennifer Chang +5 more
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, 2022 High-quality, dereplicated metagenome-assembled genomes generated from 14 long read (PacBio) and hybrid (Illumina + PacBio) assemblies. Metagenomes were generated from water column filter samples taken from the California Current.
Nastassia Patin (9109532)
core +1 more source
HISEA: HIerarchical SEed Aligner for PacBio data [PDF]
BMC Bioinformatics, 2017 The next generation sequencing (NGS) techniques have been around for over a decade. Many of their fundamental applications rely on the ability to compute good genome assemblies. As the technology evolves, the assembly algorithms and tools have to continuously adjust and improve.
Nilesh Khiste, Lucian Ilie
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