Results 211 to 220 of about 507,919 (288)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Development of a Biodegradable Polysaccharide-Based Polymer Film From <i>Hibiscus sabdariffa</i> Sepal Mucilage and Carboxymethyl Cellulose. [PDF]

Food Sci Nutr
Beigomi M, Mashhadi MA, Valizadeh M, Mashhadi FF.   +3 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Correction: An analysis of the influence of perceptual dimensions in biomimetic packaging design on generation Z consumers' flow experiences using PLS-SEM, ANN, and fsQCA. [PDF]

Sci Rep
Qi X, Wu F, Fan L.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Recent Advances in Barrier Property Enhancement of Biodegradable Polymer Films: Strategies and Challenges. [PDF]

Nanomaterials (Basel)
Huang C, Yue S, Zhong L, Huang S, Xiao M, Wang S, Han D, Meng Y.   +7 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Identification of the SARS-CoV-2 genome packaging signal in the nsp12-coding region. [PDF]

Nat Commun
Park Y, Lim J, Cho H, Son A, Jeong M, Lee YS, Kim VN.   +6 more
europepmc   +1 more source

Image-based identification and DEA-based optimization modeling of antibiotic packaging using unsupervised learning techniques. [PDF]

PLoS One
Sukpornsawan P, Meepradist Y, Auamnoy T, Suksawatchon U, Chokchaitam S, Muongmee S.   +5 more
europepmc   +1 more source