Results 141 to 150 of about 107,165 (300)

Fast Iterative Simulation of High-Speed Channelsvia Frequency-Dependent Over-Relaxation [PDF]

open access: yes, 2011
Chinea, Alessandro   +9 more
core   +1 more source

Rapid generation of replication-deficient monovalent and multivalent vaccines for bluetongue virus: protection against virulent virus challenge in cattle and sheep.

open access: yes, 2013
Since 1998, 9 of the 26 serotypes of bluetongue virus (BTV) have spread throughout Europe, and serotype 8 has suddenly emerged in northern Europe, causing considerable economic losses, direct (mortality and morbidity) but also indirect, due to ...
Hoffmann, B.   +30 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Investigation on the development and characterization of barkcloth-velvetleaf fiber composites using Taguchi-grey relational analysis for sustainable food packaging applications

open access: yesMaterials Research Express
The rising demand for biodegradable and sustainable packaging materials has generated delicate interest in natural fiber composites, with barkcloth-velvetleaf fiber composites providing a renewable alternative for food packaging applications.
Richard Tukamuhebwa   +2 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

N-terminally myristoylated feline foamy virus Gag allows Env-independent budding of sub-viral particles

open access: yes, 2011
Foamy viruses (FVs) are distinct retroviruses classified as Spumaretrovirinae in contrast to the other retroviruses, the Orthoretrovirinae. As a unique feature of FVs, Gag is not sufficient for sub-viral particle (SVP) release. In primate and feline FVs (
Löchelt, Martin   +5 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Identification of the initial nucleocapsid recognition element in the HIV-1 RNA packaging signal. [PDF]

open access: yesProc Natl Acad Sci U S A, 2020
Ding P   +16 more
europepmc   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

HIV-1 Gag protein with or without p6 specifically dimerizes on the viral RNA packaging signal. [PDF]

open access: yesJ Biol Chem, 2020
Sarni S   +7 more
europepmc   +1 more source

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