Results 131 to 140 of about 2,196,996 (280)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

HIV-1 Gag protein with or without p6 specifically dimerizes on the viral RNA packaging signal. [PDF]

open access: yesJ Biol Chem, 2020
Sarni S   +7 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Novel ways of using tobacco packaging to communicate health messages: Interviews with packaging and marketing experts

open access: yes, 2016
Background: Packaging is a powerful communications tool. In this study innovative ways in which cigarette packaging could potentially be used to communicate health messages, beyond the on-pack warnings and plain packaging, were explored. Methods: Face-to-
Moodie, Crawford
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A conceptual analysis of "shipping packaging" and "secondary packaging": Operationalizing brand loyalty theory to measure brand effects

open access: yes, 2022
With the rise of Ecommerce, more brands have an opportunity to create an "unboxing" experience for their consumers. Through "shipping" and "secondary packaging," brands have an opportunity to extend the brand's personality to a new medium and in doing so
Lukehart, Lauren
core  

Multifunctional bagasse nanocellulose-based composite films for intelligent packaging and physiology signal monitoring

open access: yesNano Research
Metabolism, transpiration, and invasion of pathogens during the storage and transportation of fruits can lead to significant waste and even food safety issues.
Qiaoyan Wei   +10 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Openability of tamperproof packaging

open access: yes, 2007
Communication, product protection and presentation are three key aspects in the world of packaging nowadays. Due to a retail landscape consisting of large stores, displaying packed products on the shelves in self-service environments, these aspects ...
Buijs, P.J. (author)   +3 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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