Results 131 to 140 of about 4,514 (233)

Panel-based Assessment of Ecosystem Condition (PAEC). Technical protocol version 2

open access: yes, 2020
Jepsen, J.U., Arneberg, P., Ims, R.A., Siwertsson, A., Yoccoz, N.G. 2020. Panel-based Assessment of Ecosystem Condition (PAEC) – Technical protocol version 2. NINA Report 1890. Norwegian Institute for Nature Research. Panel-based Assessment of Ecosystem Condition (PAEC) is a new structured protocol for assessing the condition of an ecosystem relative ...
Jepsen, Jane Uhd   +4 more
openaire   +1 more source

The molecular genetics and cellular mechanisms underlying pulmonary arterial hypertension [PDF]

open access: yes, 2012
Pulmonary arterial hypertension (PAH) is an incurable disorder clinically characterised by a sustained elevation of mean arterial pressure in the absence of systemic involvement.
Machado, Rajiv
core   +2 more sources

Cell Death in Pulmonary Arterial Hypertension

open access: yesInternational Journal of Medical Sciences
Pulmonary arterial hypertension (PAH) is a severe pulmonary vascular disease characterized by increased pulmonary vascular resistance because of vascular remodeling and vasoconstriction.
Xia Li   +5 more
semanticscholar   +1 more source

Insulin Induces Relaxation and Decreases Hydrogen Peroxide-Induced Vasoconstriction in Human Placental Vascular Bed in a Mechanism Mediated by Calcium-Activated Potassium Channels and L-Arginine/Nitric Oxide Pathways [PDF]

open access: yes, 2016
Insulin induces relaxation in umbilical veins, increasing the expression of human amino acid transporter 1 (hCAT-1) and nitric oxide synthesis (NO) in human umbilical vein endothelial cells (HUVECs). Short-term effects of insulin on vasculature have been
Andrea Saavedra   +22 more
core   +3 more sources

CDK5-mediated phosphorylation of SIRT1 at serine 47 contributes to the development of endothelial senescence [PDF]

open access: yes, 2012
ISA 2012 Monday AbstractsPoster Session 1 – Vascular Biology of Atherosclerosis: Poster no. 98: Monday abstract no. 206BACKGROUND: Senescence of endothelial cells precedes the occurrence of vascular dysfunction and promotes the development of ...
Bai, B, Vanhoutte, PM, Wang, Y
core  

NAD(P)H:quinone oxidoreductase 1 (NQO1) activity threshold in intact pulmonary arterial endothelial cells (PAEC)

open access: yesThe FASEB Journal, 2009
One pulmonary endothelial metabolic function is reduction of blood borne redox compounds via NQO1, wherein phase II enzyme induction is a potential means to optimize this function. However, a threshold above which increases in NQO1 activity do not support increases in NQO1 substrate toxicity is seen in other ...
Robert Bongard   +3 more
openaire   +1 more source

Mifepristone for preoperative treatment of uterine leiomyoma [PDF]

open access: yes, 2011
AIM: To explore the clinical impact and its molecular regulation on uterine leiomyomas in preoperative treatment with mifepristone, a progesterone receptor modulator (PRM).
Engman, Mikael
core   +1 more source

Investigation into the role of H2-Ab1 in vascular remodeling in pulmonary arterial hypertension via Bioinformatics

open access: yesBMC Pulmonary Medicine
Background Pulmonary arterial hypertension (PAH) is a progressive disease of vascular remodeling characterized by persistent pulmonary arterial pressure elevation, which can lead to right heart failure and premature death.
Guowen Wang, Zhuoyan Wang
doaj   +1 more source

Platelet-Derived Growth Factor-B (PDGF-B) Induced by Hypoxia Promotes the Survival of Pulmonary Arterial Endothelial Cells through the PI3K/Akt/Stat3 Pathway

open access: yesCellular Physiology and Biochemistry, 2015
Background/Aims: Pulmonary arterial endothelial plexiform lesions are a basic pathological change associated with pulmonary vascular remodeling and are characterized by the formation of tumorlets as a result of over-growth of endothelial cells ...
Limin Li   +9 more
doaj   +1 more source

Protective Effects of Amino Acids Against Gabexate Mesilate–Induced Cell Injury in Porcine Aorta Endothelial Cells

open access: yesJournal of Pharmacological Sciences, 2008
Gabexate mesilate (GM), a serine protease inhibitor, often causes severe vascular injury. We previously reported that GM induced necrotic cell death via injury of the cell membrane in porcine aorta endothelial cells (PAECs).
Tomoko Aki   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy