Results 191 to 200 of about 4,514 (233)

Pulmonary Artery Endothelial Cells from Patients with Pulmonary Arterial Hypertension Exhibit Heterogeneous Responses to Their Mechanical Microenvironment. [PDF]

Am J Respir Cell Mol Biol
Paudel SS, Singh N, Tambe DT, Borchert GM, Collins SA, Healey TT, Huang L, Jiao Z, Harrington EO, Stevens T, Ventetuolo CE.   +10 more
europepmc   +1 more source

New insights into pulmonary arterial hypertension: interaction between PANoptosis and perivascular inflammatory responses. [PDF]

Apoptosis
Su X, Sun Y, Dai A.
europepmc   +1 more source

Loss of Type 2 Bone Morphogenetic Protein Receptor Activates NOD-Like Receptor Family Protein 3/Gasdermin E-Mediated Pyroptosis in Pulmonary Arterial Hypertension. [PDF]

J Am Heart Assoc
Tian XT, Peng ZY, Wu YS, Cao YY, Li XC, Li Y, Tang SY, Chen AF, Li XH.   +8 more
europepmc   +1 more source

Hypoxia Combined With Interleukin-17 Regulates Hypoxia-Inducible Factor-1α/Endothelial Nitric Oxide Synthase Expression in Pulmonary Artery Endothelial Cells. [PDF]

J Cell Mol Med
Sun S, Mao J, Ding Y, Liu L, Gong J, Yang S, Li J, Kuang T, Miao R, Yang Y.   +9 more
europepmc   +1 more source

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In Vitro Modeling of RSV Infection and Cytopathogenesis in Well-Differentiated Human Primary Airway Epithelial Cells (WD-PAECs)

Methods in molecular biology, 2016
The choice of model used to study human respiratory syncytial virus (RSV) infection is extremely important. RSV is a human pathogen that is exquisitely adapted to infection of human hosts. Rodent models, such as mice and cotton rats, are semi-permissive to RSV infection and do not faithfully reproduce hallmarks of RSV disease in humans.
Broadbent, Lindsay, Villenave, Remi, Guo Parke, Hong, Douglas, Isobel, Shields, Michael, Power, Ultan   +5 more
openaire   +4 more sources

Application of TLD devices for radon and thoron PAEC measurements in air is the concept of “total PAEC” useful?

Journal of Environmental Radioactivity, 2021
The calibration of monitors of radon decay products is a difficult task, and even more so in the case of monitors detecting the products of thoron decay. An important issue here is the lack of primary standards, both in relation to the products of radon as well as thoron decay.
Stanislaw Chalupnik, Krystian Skubacz, Agata Grygier, Sandra Nowak   +3 more
openaire   +2 more sources

Molecular characterization of PRM-associated endometrial changes, PAEC, following mifepristone treatment

Contraception, 2018
The progesterone receptor modulator (PRM) mifepristone holds the potential to be developed for regular contraception. However, long-term treatment can cause thickening of the endometrium and PRM-associated endometrial changes (PAEC). The objective of this study was to explore the molecular expression of endometrium displaying PAEC after mifepristone ...
C, Berger, N, Boggavarapu, E, Norlin, S, Queckbörner, K, Hörnaeus, A, Falk, M, Engman, M, Ramström, P G L, Lalitkumar, K, Gemzell-Danielsson   +9 more
openaire   +3 more sources

Super-Enhancer-Driven HCG20 Promotes Pulmonary Hypertension Through U2AF2 Splicing.

Circulation Research
BACKGROUND Pulmonary artery endothelial cell (PAEC) dysfunction is a pathological hallmark of pulmonary hypertension (PH). Yet, the roles of long noncoding RNAs (lncRNAs) driven by super-enhancers (SEs) in PAECs are not well understood. In this study, we
Jian Mei, Wei Huang, Zitong Meng, Shiqing Wen, Langlin Ou, June Bai, Xiaoying Wang, Hao Yuan, Yanyu Li, Lixin Zhang, Yuwei You, Yingli Chen, Xiaodong Zheng, Fei Li, Song Wang, Xiangrui Zhu, Zhaosi Wang, Daling Zhu, Xiaowei Nie, Cui Ma   +19 more
semanticscholar   +1 more source

Deficient FANCL Predisposes Endothelial Damage: A New Therapeutic Target for Pulmonary Hypertension.

American Journal of Respiratory and Critical Care Medicine
RATIONALE Clinical observations have suggested an association between alkylating agents-based chemotherapy and pulmonary arterial hypertension (PAH). The Fanconi anemia (FA) pathway, principal mechanism for resolving alkylating agent-induced DNA damage ...
Shiyun Liu, Xiaoqian Shan, Yufei Sun, Haixia Chen, Huazhuo Feng, Shaocong Mo, Changlei Bao, Junqi Zhu, Zizhou Zhang, Feng Wei, Xiuzhen Bai, Ran Xu, Jiaxuan Lai, Haiyun Luo, Chenting Zhang, Xiaoyun Luo, Qian Jiang, Yuqin Chen, Yuqi Zhou, Haiyang Tang, Lei Xu, Wenju Lu, Rong Guo, Chunli Liu, Zifeng Yang, Jason X.-J. Yuan, Xinlin Xu, Dongyi Xu, Jian Wang, Kai Yang   +29 more
semanticscholar   +1 more source

The Role of Ion Channels in Pulmonary Hypertension: A Review

Pulmonary Circulation
Pulmonary hypertension (PH) constitutes a critical challenge in cardiopulmonary medicine with a pathogenesis that is multifaceted and intricate.
Han-Fei Li, Xin-Yao Li, Yu-Qing Sun, Ze‐Ying Zhi, Liao-fan Song, Meng Li, Yi-Ming Feng, Zhi-Hao Zhang, Yan-Feng Liu, Yu-jing Chen, Fan-rong Zhao, Tian-tian Zhu   +11 more
semanticscholar   +1 more source