Results 71 to 80 of about 4,514 (233)
Role of noncoding RNA in vascular remodelling [PDF]
, 2016 Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H. +2 more
core +1 more source
Transcriptional profiles of pulmonary artery endothelial cells in pulmonary hypertension
Scientific Reports, 2023 Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether differential gene expression of pulmonary artery ECs (PAECs) can discern disease subtypes, progression ...
Navneet Singh +16 more
semanticscholar +1 more source
Transcription factors and potential therapeutic targets for pulmonary hypertension
Frontiers in Cell and Developmental Biology, 2023 Pulmonary hypertension (PH) is a refractory and fatal disease characterized by excessive pulmonary arterial cell remodeling. Uncontrolled proliferation and hypertrophy of pulmonary arterial smooth muscle cells (PASMCs), dysfunction of pulmonary arterial ...
Liu Yang +5 more
doaj +1 more source
Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1 [PDF]
, 2018 Sphingosine kinase 1 (SphK1) upregulation is associated with pathologic pulmonary vascular remodeling in pulmonary arterial hypertension (PAH), but the mechanisms controlling its expression are undefined.
Chen, Jiwang +6 more
core +1 more source
AGRICULTURE AND BIOTECHNOLOGY CENTRES OF THE PAEC: A RESUME
The Nucleus, 2020 Pakistan recognized the role of nuclear techniques in agricultural and other biological research and started establishing goal-oriented, multi- disciplinary institutions to help agricultural research in the country. A core manpower was trained and centres established in the cities where most of the agricultural research was located; the objective was ...
openaire +1 more source
Vascular Remodeling: The Multicellular Mechanisms of Pulmonary Hypertension
International Journal of Molecular SciencesPulmonary hypertension (PH) is a serious cardiovascular disease caused by a variety of pathogenic factors, which is characterized by increased pulmonary vascular resistance (PVR) and progressive elevation of mean pulmonary artery pressure (mPAP).
Jinjin Dai +4 more
semanticscholar +1 more source
Targeting Vascular Remodeling to Treat Pulmonary Arterial Hypertension [PDF]
, 2017 Pulmonary arterial hypertension (PAH) describes a group of conditions with a common hemodynamic phenotype of increased pulmonary artery pressure, driven by progressive remodeling of small pulmonary arteries, leading to right heart failure and death ...
Lawrie, A., Thompson, A.A.R.
core +1 more source
Immunology, EarlyView.This study shows that 8 weeks of high‐intensity interval training (HIIT) modulate inflammasome‐related gene expression in individuals with obesity. HIIT increased AIM2, MEFV, CARD16 and CARD18 expression, with CARD16 upregulation supporting reduced inflammation through inhibition of caspase‐1 activation and lower IL‐1β levels.
Ana Luíza Pereira Assunção Silveira +8 more
wiley +1 more source
CONTRIBUTIONS OF PROFESSOR ABDUS SALAM AS MEMBER OF PAEC
The Nucleus, 2020 The contributions of Prof. Abdus Salam in Physics and for development of Science in Pakistan and developing countries are highlighted. In particular those which he made as a member of PAEC are discussed in some detail.
openaire +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Inwardly rectifying (Kir2) and ATP‐sensitive (KATP) potassium channels are functionally expressed in human pulmonary artery endothelial and smooth muscle cells. The schematic illustrates how Kir2‐ and KATP‐mediated K+ efflux contributes to VM regulation and pulmonary vascular tone.
Bianca Barreira +7 more
wiley +1 more source