Results 81 to 90 of about 4,514 (233)

Protective role of FKBP51 in calcium entry-induced endothelial barrier disruption

Pulmonary Circulation, 2018
Pulmonary artery endothelial cells (PAECs) express a cation current, I SOC (store-operated calcium entry current), which when activated permits calcium entry leading to inter-endothelial cell gap formation.
Caleb L. Hamilton, Pierre I. Kadeba, Audrey A. Vasauskas, Viktoriya Solodushko, Anna K. McClinton, Mikhail Alexeyev, Jonathan G. Scammell, Donna L. Cioffi   +7 more
doaj   +1 more source

Engineering Functional Vasculature in Decellularized Lungs Depends on Comprehensive Endothelial Cell Tropism

Frontiers in Bioengineering and Biotechnology, 2021
Tissue engineering using decellularized whole lungs as matrix scaffolds began as a promise for creating autologous transplantable lungs for patients with end-stage lung disease and can also be used to study strategies for lung regeneration ...
Ifeolu Akinnola, Daniel R. Rossi, Carolyn Meyer, Ashley Lindsey, Douglas R. Haase, Samuel Fogas, Michael J. Ehrhardt, Rachel E. Blue, Andrew. P. Price, Max Johnson, Diego F. Alvarez, Doris A. Taylor, Angela Panoskaltsis-Mortari, Angela Panoskaltsis-Mortari   +13 more
doaj   +1 more source

Effects of a novel estrogen-free, progesterone receptor modulator contraceptive vaginal ring on inhibition of ovulation, bleeding patterns and endometrium in normal women [PDF]

, 2012
BACKGROUND: Progesterone receptor modulators (PRMs) delivered by contraceptive vaginal rings provide an opportunity for development of an estrogen-free contraceptive that does not require daily oral intake of steroids.
Blithe, Diana, Brache, Vivian, Cochon, Leila, Croxatto, Horacio, Faundes, Anibal, Kumar, Narender, Kumar, Sushma, Miranda, Maria Jose, Mishell, Daniel, Nath, Anita, Reyes, Verónica, Sitruk-Ware, Regine, Sivin, Irving, Sussman, Heather, Tsong, Yun-Yen, Williams, Alistair   +15 more
core   +1 more source

DR. I.H. USMANI AND THE EARLY DAYS OF THE PAEC

The Nucleus, 2020
Combining a scientific background with the power of a senior civil servant, Dr. I.H. Usmani laid a sound foundation of the atomic energy programme in Pakistan. First he developed top quality manpower. He recruited the best graduates of Pakistani universities, arranged their training at world famous universities and nuclear establishments.
openaire   +1 more source

Estudiantes bolivianos de posgrado en el Programa “Becas Brasil” PAEC-OEA – GCUB 2011-2021

Revista Educación Superior y Sociedad (ESS), 2022
Este trabajo tuvo como propósito observar, describir e interpretar algunas de las principales características de la participación de estudiantes bolivianos en el programa Becas Brasil PAEC-OEA - GCUB (2011-2021) que concediera becas de maestría y doctorado.
openaire   +1 more source

ROC‐325 Attenuates Hypoxia‐Induced Pulmonary Hypertension Through Dual Inhibition of Autophagy and Hypoxia‐Inducible Factor 2α Signaling

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
In hypoxia‐induced pulmonary hypertension, endothelial HIF‐2α accumulation and autophagic activation drive vascular remodeling. We demonstrate that the novel lysosomal inhibitor ROC‐325 simultaneously attenuates this pathogenic autophagy and promotes HIF‐2α degradation.
Changlei Bao, Shuxin Liang, Dingyuan Liu, Xingting Wang, Dan Bai, Chuangjia Huang, Hanliang Sun, Zi Yang, Bitao Wu, Zixuan Chen, Jieyi Feng, Zinan Luo, Jintao Long, Jinsheng Zhu, June Bai, Li Zhang, Aiai Chu, Caojin Zhang, Haiyang Tang   +18 more
wiley   +1 more source

Actin-binding rho activating protein (Abra) is essential for fluid shear stress-induced arteriogenesis [PDF]

, 2009
OBJECTIVE: Arteriogenesis, the development of a collateral circulation, is important for tissue survival but remains functionally defective because of early normalization of fluid shear stress (FSS).
Apfelbeck, H., Cai, W.J., Grossekettler, L., Grote, K., Horrevoets, A.J.G., Mucke, Y., Piotrowska, I., Ruding, I., Schaper, W., Schierling, W., Schmitz-Rixen, T., Troidl, C., Troidl, K., Volger, O.L.   +13 more
core   +2 more sources

Medicina y magia entre los paeces

Revista Colombiana de Antropología, 1954
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openaire   +2 more sources

Endothelial Upregulation of Mechanosensitive Channel Piezo1 in Pulmonary Hypertension.

American Journal of Physiology - Cell Physiology, 2021
Piezo is a mechanosensitive cation channel responsible for stretch-mediated Ca2+ and Na+ influx in multiple types of cells. Little is known about the functional role of Piezo1 in the lung vasculature and its potential pathogenic role in pulmonary ...
Ziyi Wang, Jiyuan Chen, A. Babicheva, P. Jain, Marisela Rodriguez, R. Ayon, K. Ravellette, Linda Wu, F. Balistrieri, Haiyang Tang, Xiaomin Wu, Tengteng Zhao, S. Black, A. Desai, Joe G. N. Garcia, Xin Sun, J. Shyy, D. Valdez-Jasso, P. Thistlethwaite, A. Makino, Jian Wang, J. Yuan   +21 more
semanticscholar   +1 more source

The hepcidin‐ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells

Pulmonary Circulation
Elevated circulating hepcidin levels have been reported in patients with pulmonary artery hypertension (PAH). Hepcidin has been shown to promote proliferation of human pulmonary artery smooth muscle cells (PASMCs) in vitro, suggesting a potential role in
Theo Issitt, Quezia K. Toe, Sofia L. Pedersen, Thomas Shackshaft, Maziah Mohd Ghazaly, Laura West, Nadine D. Arnold, Abdul Mahomed, George W. Kagugube, Latha Ramakrishnan, Allan Lawrie, Gregory J. Quinlan, S. John Wort   +12 more
doaj   +1 more source