Results 71 to 80 of about 4,897 (175)

Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine

Drug Design, Development and Therapy, 2020
Xuan Zou,1,2,* Yang Wang,1,2,* Yuheng Wang,3 Junting Yang,3 Huishu Guo,1,2 Zhengxu Cai3 1Central Laboratory, The First Affiliated Hospital of Dalian Medical University, Dalian 116001, People’s Republic of China; 2Institute (College) Integrative ...
Zou X, Wang Y, Wang Y, Yang J, Guo H, Cai Z   +5 more
doaj  

Dose-Dependent Pharmacokinetics of Paeoniflorin in Rats.

Drug Metabolism and Pharmacokinetics, 1990
The pharmacokinetics of paeoniflorin (PAE) was examined after an iv dose of 20, 40, or 100mg/kg in rats. The decline of plasma concentration was biexponential after each dose. Dose, however, had a marked effect on the pharmacokinetics, with a greater than proportional increase in AUC at 100mg/ kg, even though the increase was proportional at the dose ...
ISHIDA, Shiro, SAKIYA, Yoko, ICHIKAWA, Tsutomu   +2 more
openaire   +2 more sources

Determination of total flavonoids， total polyphenols， paeoniflorin and antioxidant activity in twenty varieties of peony leaves

Siliao yanjiu, 2023
The experiment was to determine the content of total flavonoids, total phenols and paeoniflorin in 20 peony leaves and their antioxidant activity.The total flavonoids and total phenols were determined by ultraviolet spectrophotometry and paeoniflorin was
NING Er-juan, CHEN Ling, WANG Xue-fang, ZHANG Li-pan, WANG Fa-yun, LI Xiao   +5 more
doaj  

Influence of paeoniflorin dietary supplementation on growth performance, antioxidant status, blood parameters, carcass characteristics and meat quality in broiler chickens

Veterinary and Animal Science
Paeonia lactiflora Pall, known for its antioxidative and anti-apoptotic properties, is a traditional Chinese medicine. To address the growing demand for animal protein, large-scale commercial broiler production systems often induce excessive stress ...
Yefei Zhou, Cunyi Qiu, Zhiding Zhou, Dunlin Zhang, Yao Cai, Jun Yuan, Shanguo Mao   +6 more
doaj   +1 more source

Paeoniflorin ameliorates chronic colitis via the DR3 signaling pathway in group 3 innate lymphoid cells

Journal of Pharmaceutical Analysis
Inhibiting the death receptor 3 (DR3) signaling pathway in group 3 innate lymphoid cells (ILC3s) presents a promising approach for promoting mucosal repair in individuals with ulcerative colitis (UC).
Shaowei Huang, Xueqian Xie, Bo Xu, Zengfeng Pan, Junjie Liang, Meiling Zhang, Simin Pan, Xiaojing Wang, Meng Zhao, Qing Wang, Jinyan Chen, Yanyang Li, Lian Zhou, Xia Luo   +13 more
doaj   +1 more source

Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain

Journal of Neuroinflammation, 2019
Background Neuropathic pain is a serious clinical problem that needs to be solved urgently. ASK1 is an upstream protein of p38 and JNK which plays important roles in neuroinflammation during the induction and maintenance of chronic pain.
Danli Zhou, Siqi Zhang, Liang Hu, Yu-Feng Gu, Yimei Cai, Deqin Wu, Wen-Tao Liu, Chun-Yi Jiang, Xiangqing Kong, Guang-Qin Zhang   +9 more
doaj   +1 more source

Interaction of the Main Components from the Traditional Chinese Drug Pair Chaihu-Shaoyao Based on Rat Intestinal Absorption

Molecules, 2011
The Chaihu-Shaoyao drug pair (Bupleuri Radix and Paeoniae Radix Alba) which is a traditional Chinese drug pair, has been widely used for anti-inflammatory purposes.
Xiaobin Tan, Xiaobin Jia, Ling Yuan, Yan Chen, Jinyan Wang, Lei Zhou   +5 more
doaj   +1 more source

Paeoniflorin-Inflammatory injury

Paeoniflorin Alleviates Inflammatory Injury in Mastitis by Targeting AKT1-Mediated Mitochondrial Damage and Epithelial Cell ...
openaire   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Cholinesterase Inhibitory Activity of Paeoniflorin: Molecular Dynamics Simulation, and In Vitro Mechanistic Investigation

Biochemistry Research International
Alzheimer’s disease (AD), a neurological disorder, is one of the major reasons for memory loss in the world. AD is characterized by a sequela of cognitive and functional decline caused by brain cell degeneration. Paeoniflorin is a monoterpenoid glycoside
Mohnad Abdalla, Asaad Khalid, Jasmine Hedayati, Muhammad Nabeel Ghayur   +3 more
doaj   +1 more source