Results 51 to 60 of about 4,897 (175)
Promoting neurogenesis in hippocampal dentate gyrus of chronic unpredictable stress-induced depressive-like rats with paeoniflorin [PDF]
Journal of Integrative Neuroscience, 2019 Hippocampal neurogenesis plays an important role in the onset and treatment of depressive disorders. Previous studies suggest that paeoniflorin could be used as an antidepressant for treating rats subjected to chronic unpredictable stress. In this study,
Li-Bing Chen, Feng-Mei Qiu, Xiao-Ming Zhong, Cheng Hong, Zhen Huang
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Advanced Science, Volume 13, Issue 36, 29 June 2026.A bioactive hydrogel incorporating Chlorella vulgaris and paeoniflorin within a carboxymethyl chitosan/sodium alginate matrix cross‐linked with genipin is developed for inflammatory bowel disease therapy. The hydrogel exhibits gastric stability and intestine‐responsive release.
Jing Lu +8 more
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Paeoniflorin Enhances Endometrial Receptivity through Leukemia Inhibitory Factor
Biomolecules, 2021 Despite advances in assisted reproductive technology, treatment for deficient endometrial receptivity is a major clinical unmet need. In our previous study, the water extract of Paeonia lactiflora Pall.
Hye-Rin Park +8 more
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Intranasal delivery of paeoniflorin nanocrystals for brain targeting
Asian Journal of Pharmaceutical Sciences, 2020 Paeoniflorin (PA) is an anti-Parkinson Chinese medicine with inferior bioavailability and difficulty in delivery to the brain. This research is to develop an efficacious PA nanocrystal formulation (PA-NCs) that is suitable for intranasal administration to treat Parkinson's disease (PD). PA-NCs were fabricated through an antisolvent precipitation method
Chaoyin Wu +7 more
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AgriFood: Journal of Agricultural Products for Food, Volume 2, Issue 2, Page 127-140, June 2026.The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang +6 more
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Brain and Behavior, Volume 16, Issue 6, June 2026.In treating Qi stagnation type insomnia, the combination of traditional Chinese medicine and acupuncture can improve sleep quality, alleviate anxiety and depression, and improve physical fitness. Compared to using traditional Chinese medicine decoction alone for treatment, the combination of traditional Chinese medicine decoction and acupuncture has ...
Xue‐Wen Mao, Peng Bai
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The analgesic effect of paeoniflorin: A focused review
Open Life SciencesAbstract Pain has been a prominent medical concern since ancient times. Despite significant advances in the diagnosis and treatment of pain in contemporary medicine, there is no a therapeutic cure for chronic pain. Chinese herbaceous peony, a traditional Chinese analgesic herb has been in clinical use for millennia, with widespread ...
Li Mingzhu +6 more
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Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis
eFood, Volume 7, Issue 3, June 2026.Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng +5 more
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Exploration, Volume 6, Issue 3, June 2026.The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng +10 more
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Molecules, 2012 Shaoyao-Gancao (Paeoniae Radix Alba and Glycyrrhizae Radix et Rhizoma) is a traditional Chinese drug pair widely used in decoctions for relieving pains, especially abdominal pain.
Qingqing Wu +4 more
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