Results 31 to 40 of about 4,897 (175)
The Study of a Novel Paeoniflorin-Converting Enzyme from Cunninghamella blakesleeana
Molecules, 2023 Paeoniflorin is a glycoside compound found in Paeonia lactiflora Pall that is used in traditional herbal medicine and shows various protective effects on the cardio-cerebral vascular system.
Yiheng Ye +7 more
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Frontiers in Pharmacology, 2019 Objectives: Asthma is a chronic airway inflammatory disease, which is characterized by airway remodeling, hyperreactivity and shortness of breath. Paeoniflorin is one of the major active ingredients in Chinese peony, which exerts anti-inflammatory and ...
Qiyang Shou +12 more
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Frontiers in Pharmacology, 2022 Objective: Major depressive disorder (MDD) is one of the most common psychiatric disorders, the diagnosis and treatment of MDD are major clinical issues. However, there is a lack of effective biomarkers and drugs diagnosis and therapeutics of MDD. In the
Sha Zhang +7 more
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Journal of Pharmacological Sciences, 2005 The root of Paeonia lactiflora and the stem of Sinomenium acutum are two herbs widely used in Chinese herbal medicine for the treatment of inflammatory and arthritic diseases.
Zhong Qiu Liu +7 more
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Frontiers in Psychiatry, 2019 Neuronal damage is related to the onset and treatment of depressive disorders. Antidepressant-like effects have been elicited by paeoniflorin on animal models.
Xiaoming Zhong +3 more
doaj +1 more source
Neuroprotection of paeoniflorin as antidepressant candidate
BioMedicineBackground: Depression is one of the common mental disorders worldwide, and currently used antidepressants have undesirable effects; therefore, the development of new antidepressants without side effects is urgently needed. Paeoniflorin (PF) exhibits various pharmacological activities, including anti-inflammatory, antioxidant, and neuroprotective ...
Chen, Yuh-Fung +4 more
openaire +3 more sources
eFood, Volume 7, Issue 4, August 2026.Schematic diagram of the mechanism by which Moutan Cortex extract (MCE) ameliorates DR. MCE alleviates retinal structural damage and reduces neovascular lesions by downregulating the ROS/HIF‐1α/VEGF signaling axis. ABSTRACT Moutan Cortex is a functional food ingredient with multiple health benefits, but its effects on diabetic retinopathy (DR) remain ...
Mei‐rong Li +13 more
wiley +1 more source
Pakistan Journal of Pharmaceutical Sciences, 2020 Paeoniflorin and amygdalin are two major active saponins constituents in some Chinese herbal formulas used for cardio-cerebrovascular diseases. However, their intestinal absorption property and metabolic characteristics have not been clarified.
Huifen Zhou +5 more
doaj +1 more source
Food Science &Nutrition, Volume 14, Issue 8, August 2026.Evidence from 10 preclinical studies involving 181 rodents indicates that paeoniflorin may alleviate several features of nonalcoholic fatty liver disease, including dyslipidemia, impaired glucose metabolism, liver injury, inflammation, and oxidative stress.
Dachuan Jin +7 more
wiley +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source