Results 1 to 10 of about 2,702,692 (201)
Calcified Tissue International, 1977 Paget’s disease of bone is a focal disorder of unknown etiology characterized initially by excessive resorption and subsequently by excessive formation of bone, culminating in a “mosaic” pattern of lamellar bone associated with extensive local vascularity and increased fibrous tissue in adjacent marrow.
Frederick R. Singer, Stephen M. Krane
+13 more sources
Best Practice & Research Clinical Endocrinology & Metabolism, 2018 Paget's disease of bone is a focal disorder of bone remodelling that progresses slowly and leads to changes in the shape and size of affected bones and to skeletal, articular and vascular complications. In some parts of the world it is the second most common bone disorder after osteoporosis though in recent years its prevalence and severity appear to ...
Appelman-Dijkstra, N.M. +1 more
+9 more sources
Paget??s disease of bone [PDF]
Current Opinion in Rheumatology, 1997 The highest incidence of Paget's disease is in the United Kingdom and is lower in other European countries. Worldwide the incidence appears to be decreasing. Some countries have observed a reduction in the severity at presentation, perhaps reflecting changes in migration of the UK population.
William D. Fraser, C. G. Ooi
+11 more sources
Clinical Endocrinology News, 2006 Paget's disease of bone is a focal disorder of bone remodeling accompanied initially by an increase in bone resorption, followed by a disorganized and excessive formation of bone, leading to pain, fractures and deformities. It exhibits a marked geographical variation in its prevalence. In Brazil it predominantly affects persons of European descent. The
Lora T. McGlade, Elizabeth Mechcatie
openaire +5 more sources
Pagetoid spread of urothelial carcinoma controlled without resection
IJU Case Reports, Volume 6, Issue 1, Page 65-69, January 2023., 2023 Introduction Extramammary Paget's disease is an eczematous skin condition that affects the vulva and perineum. Extramammary Paget's disease secondary to urothelial carcinoma is a rare condition that is typically treated with invasive surgical resection of the lesion.
Shutaro Yamamoto +9 more
wiley +1 more source
DIAGNOSIS AND MANAGEMENT OF PAGET'S DISEASE OF BONE - SERIES OF 8 CASES [PDF]
Acta Ortopédica Brasileira, 2019 Paget's disease of bone is a chronic condition characterized by focal abnormalities of absorption and formation of bone, and it may lead to anatomical deformities, pain, fractures, and malignant transformation.
Felipe Augusto Kazan de Oliveira +5 more
doaj +1 more source
Paget's disease of bone in Tunisia: A study of 69 patients
Indian Journal of Endocrinology and Metabolism, 2020 Context: Paget's disease of bone is a common bone disease with a striking variation in its incidence and characteristics in different parts of the world. It is uncommonly reported in African patients.
Kaouther Maatallah +8 more
doaj +1 more source
Journal of Clinical Investigation, 2005 Paget disease of bone (PD) is characterized by excessive bone resorption in focal areas followed by abundant new bone formation, with eventual replacement of the normal bone marrow by vascular and fibrous tissue. The etiology of PD is not well understood, but one PD-linked gene and several other susceptibility loci have been identified, and ...
Jolene J. Windle, G. David Roodman
openaire +2 more sources
Histopathology, Volume 82, Issue 2, Page 276-284, January 2023., 2023 Primary cutaneous apocrine carcinoma (PCAC) is a rare cutaneous malignancy that is derived from apocrine glands. Histologically, these tumours can appear well‐differentiated where diagnosis should be relatively straightforward. However, occasionally these tumours can exhibit high‐grade features, and in such instances the diagnosis can be challenging. A
Jose A Plaza +5 more
wiley +1 more source
Paget's disease of bone in the patient presented with a bowed leg
Clinical Case Reports, 2023 Key Clinical Message In dealing with bowed limbs along with increased alkaline phosphatase (ALP), even if the typical changes to the face are not very noticeable at first glance, Paget's disease of the bone (PDB) should be suspected, and the necessary ...
Mehrzad Hajialiloo +1 more
doaj +1 more source