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Paget's disease of bone in the patient presented with a bowed leg [PDF]
Clinical Case Reports, 2023 Key Clinical Message In dealing with bowed limbs along with increased alkaline phosphatase (ALP), even if the typical changes to the face are not very noticeable at first glance, Paget's disease of the bone (PDB) should be suspected, and the necessary ...
Mehrzad Hajialiloo +1 more
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Updates on Paget’s Disease of Bone [PDF]
Endocrinology and Metabolism, 2022 Paget’s disease of the bone is a prevalent bone disease characterized by disorganized bone remodeling; however, it is comparatively uncommon in East Asian countries, including China, Japan, and Korea. The exact cause still remains unknown. In genetically
Yong Jun Choi +2 more
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Paget's disease of bone in Tunisia: A study of 69 patients [PDF]
Indian Journal of Endocrinology and Metabolism, 2020 Context: Paget's disease of bone is a common bone disease with a striking variation in its incidence and characteristics in different parts of the world. It is uncommonly reported in African patients.
Kaouther Maatallah +8 more
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Radiological impact of oral bisphosphonate use on polyostotic Paget's disease of bone over a 2 year period [PDF]
Radiology Case ReportsPaget's disease of bone is a disorder of osteoclasts which hampers the physiological process of bone remodeling. It is the most common metabolic orthopedic disease in the Caucasian populace; we report the diagnosis of Paget's disease of bone in a South ...
Christopher Jude Pinto, MD +3 more
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Paget’s Disease of Bone and Normocalcemic Variant of Primary Hyperparathyroidism in an Osteoporotic Male: Exceptional Coexistence [PDF]
ReportsBackground and clinical significance: Paget’s disease of bone involves anomalies of the bone metabolism; however, the presence of tumor-derivate abnormal parathyroid hormone (PTH) levels does not represent one of these disturbances. To our best knowledge,
Ana-Maria Gheorghe +4 more
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Functional bracing for delayed union of a femur fracture associated with Paget's disease of the bone in an Asian patient: a case report [PDF]
Journal of Orthopaedic Surgery and Research, 2010 Paget's disease of the bone is a common metabolic bone disease in most European countries, Australia, New Zealand, and North America. Conversely, this disease is rare in Scandinavia, Asia, and Africa.
Fukuta Masashi +4 more
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Adult Paget's disease of bone [PDF]
Clinical Medicine, 2020 Adult Paget's disease of bone is the second commonest metabolic bone condition after osteoporosis. The condition is characterised by increased bone cell activity, with bone-resorbing osteoclasts often larger and containing more nuclei than normal and osteoblasts producing increased amounts of disorganised bone.
Stephen P, Tuck, Julie, Walker
openaire +3 more sources
Postgraduate Medical Journal, 1997 SummaryPaget's disease of bone is a relatively common condition in the UK affecting up to 5% of the population over the age of 55 years with particularly high prevalence in the North West of England. The majority of those affected are asymptomatic. Its precise cause remains unknown, and until recently, choice of treatment of this sometimes painful and ...
C G, Ooi, W D, Fraser
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Calcified Tissue International, 1977 Paget’s disease of bone is a focal disorder of unknown etiology characterized initially by excessive resorption and subsequently by excessive formation of bone, culminating in a “mosaic” pattern of lamellar bone associated with extensive local vascularity and increased fibrous tissue in adjacent marrow.
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Journal of Clinical Investigation, 2005 Paget disease of bone (PD) is characterized by excessive bone resorption in focal areas followed by abundant new bone formation, with eventual replacement of the normal bone marrow by vascular and fibrous tissue. The etiology of PD is not well understood, but one PD-linked gene and several other susceptibility loci have been identified, and ...
G David, Roodman, Jolene J, Windle
openaire +2 more sources