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DIAGNOSIS AND MANAGEMENT OF PAGET'S DISEASE OF BONE - SERIES OF 8 CASES [PDF]
Acta Ortopédica Brasileira, 2019 Paget's disease of bone is a chronic condition characterized by focal abnormalities of absorption and formation of bone, and it may lead to anatomical deformities, pain, fractures, and malignant transformation.
Felipe Augusto Kazan de Oliveira +5 more
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Trauma Case Reports, 2021 Introduction: Paget's disease of the bone is a non-malignant skeletal disorder characterized by focal abnormalities in bone remodelling at one or more skeletal sites.
Marjan Raad +4 more
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Severe congestive heart failure in elderly patient with Paget’s disease
Geriatric Care, 2017 Paget’s disease of bone is characterized by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton. Paget’s disease is often asymptomatic, but can be associated with bone pain and other skeletal and non-skeletal ...
Lorenzo Palleschi, Eleonora Nunziata
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Türk Osteoporoz Dergisi, 2020 Paget’s disease of bone is characterized by a chronic focal bone remodelling disorder, which is usually detected incidentally during routine imagining examinations.
Gonca Sağlam
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The Journal of Bone and Joint Surgery. British volume, 1979 This chapter focuses on Paget's disease of bone. The pathological hallmark of the Paget's bone disease is excessive and disorganized activity of bone that involves both matrix and mineral. There is no idea of its cause and little knowledge of its natural history; however, the biochemical changes produced by the overactive bone justify its inclusion as ...
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New England Journal of Medicine, 1993 Paget's disease of bone may present with bone pain but is often asymptomatic. Treatment (typically with bisphosphonates) is indicated in patients with pain that is localized to an affected site but not in asymptomatic patients.
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Expert Review of Endocrinology & Metabolism, 2009 Paget's disease of bone is a focal bone disorder that is common among older people of Western European descent. It is an unusual disorder, for although we now have safe and highly effective treatment, there are many aspects of its pathogenesis and natural history that we do not yet understand.
Brya, Matthews, Tim, Cundy
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Tumor-Associated Hypercalcemia in a Patient with Paget's Disease
Kaohsiung Journal of Medical Sciences, 2008 Paget's disease of the bone, which is characterized by a focal region of highly exaggerated bone remodeling, is very rare in Asia. Most patients with Paget's disease are asymptomatic; they are normocalcemic and show elevated alkaline phosphatase levels ...
Hao-Chang Hung +4 more
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Paget’s disease of bone: A rare case in a patient under 40 years of age
Human Pathology Reports, 2021 Paget’s disease of bone is a rare diagnosis in patients under 40 years of age. We report a case diagnosed in a 35-year-old patient with suspected symptomatic presentation at the age of 30 years during pregnancy.
Erina Melva McKinney +4 more
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Optineurin functions for optimal immunity [PDF]
, 2018 Optineurin (OPTN) was identified 20 years ago in a yeast-two-hybrid screen with a viral protein known to inhibit the cytolytic effects of tumor necrosis factor.
Slowicka, Karolina, van Loo, Geert
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