Results 21 to 30 of about 9,984 (217)

Acquired Chiari Type 1 Malformation Secondary to Paget’s Disease of the Bone: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Chiari type 1 malformations are characterised by caudal descent of cerebellar tonsil into foramen magnum. Usually it is congenital. Paget’s disease causing acquired chiari type 1 malformation is rare with only five reported cases in the literature.
Srestha Khan   +3 more
doaj   +1 more source

Boning up on autophagy: the role of autophagy in skeletal biology. [PDF]

open access: yes, 2013
From an evolutionary perspective, the major function of bone is to provide stable sites for muscle attachment and affording protection of vital organs, especially the heart and lungs (ribs) and spinal cord (vertebrae and intervertebral discs).
Layfield, Robert   +4 more
core   +2 more sources

Paget's disease of bone [PDF]

open access: yesBest Practice & Research Clinical Endocrinology & Metabolism, 2018
Paget's disease of bone is a focal disorder of bone remodelling that progresses slowly and leads to changes in the shape and size of affected bones and to skeletal, articular and vascular complications. In some parts of the world it is the second most common bone disorder after osteoporosis though in recent years its prevalence and severity appear to ...
Appelman-Dijkstra, N.M.   +1 more
openaire   +5 more sources

Long-term randomized trial of intensive versus symptomatic management in Paget's disease of bone: The PRISM-EZ study [PDF]

open access: yes, 2017
It has been suggested that normalization of bone turnover may improve clinical outcome in Paget’s disease of bone (PDB) by preventing complications such as fractures and the progression of osteoarthritis.
Armamento-Villareal   +23 more
core   +2 more sources

Five-year follow-up of Japanese patients with Paget's disease of the bone after treatment with low-dose oral alendronate: a case series

open access: yesJournal of Medical Case Reports, 2010
Introduction Paget's disease of the bone is characterized by focal abnormalities of increased bone turnover affecting one or more sites throughout the skeleton.
Wada Takuro   +3 more
doaj   +1 more source

Paget’s disease of bone [PDF]

open access: yesQJM, 2014
Paget's disease is an osteoclastic-mediated disorder of bone that results in abnormal bone resorption associated with inadequate remodeling that leads to mechanically weakened bone. Demonstrating variable geographic prevalence, it is becoming less frequent and age of onset is lengthening in areas of once high prevalence prior to the institution of ...
Gregory, Gruener, Pauline, Camacho
openaire   +4 more sources

PAGET’S DISEASE OF THE BONE: AN UNUSUAL CAUSE OF LOW BACK PAIN IN AN ADULT MALE [PDF]

open access: yesRomanian Journal of Rheumatology, 2016
Paget’s disease of the bone (PDB) or osteitis deformans is a chronic metabolic bone disorder, characterized by focal increase in bone resorption, followed by a rapid and abnormal bone repair with a disorganized and excessive bone formation, leading to ...
Iulian Resmerita   +2 more
doaj   +1 more source

A rare case of orbital osteogenic sarcoma [PDF]

open access: yes, 1996
Osteogenic sarcoma is a malignant bony tumor of mesenchymal cell ori gin. The association of osteogenic sarcoma with Paget's disease of the bone (osteitis deformans) is well-known.
Fry, CL   +3 more
core   +1 more source

A Case of Paget’s Disease with Scapula Involvement

open access: yesTürk Osteoporoz Dergisi, 2015
Paget’s disease is a common bone disorder which is characterized by excessive bone turnover. This condition rarely involves sternum, patella, scapula, hand, foot and facial bones. A 65-year-old male patient was admitted to our outpatient clinic with the
Nilgün Mesci   +3 more
doaj   +1 more source

Paget’s Disease of Maxilla with Paranasal Sinuses: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Paget’s disease of bone is a chronic skeletal disorder affecting predominantly elderly individuals. The pelvic girdle is the most common site to be affected; however, other sites such as long bones, spine, and skull are also frequently affected.
Amurtham Veeramani   +4 more
doaj   +1 more source

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