Results 21 to 30 of about 2,702,692 (201)
Modelling the anabolic response of bone using a cell population model [PDF]
J Theor Biol 307 (2012) 42-52, 2011 To maintain bone mass during bone remodelling, coupling is required between bone resorption and bone formation. This coordination is achieved by a network of autocrine and paracrine signalling molecules between cells of the osteoclast lineage and cells of the osteoblastic lineage.
arxiv +1 more source
Paget's disease of the skull causing hyperprolactinemia and erectile dysfunction: a case report
Journal of Medical Case Reports, 2008 Introduction Hyperprolactinemia is an uncommon cause of erectile dysfunction in men. Paget's disease of the skull is a relatively common disease. This case proposes a rare example of a causative link between the two and how treatment of the Paget's ...
Hepherd Rachel, Jennings Paul E
doaj +1 more source
BMJ, 1981 The essential requirement for effective treatment of Paget’s disease of bone is that the characteristic abnormality of bone remodelling is predictably corrected without the occurrence of significant side effects. Although the ideal agent is not currently available, appropriate use of the calcitonins or diphosphonates goes a long way to achieving this ...
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Paget's disease of bone: A rare case report
Journal of Indian Academy of Oral Medicine and Radiology, 2020 Paget's disease of bone (PDB) is a localized bone remodeling disorder that is chronic, non-inflammatory.. It is also known as “osteodystrophia deformans” as described by Sir James Paget. PDB is the second most common bone disease after osteoporosis. This
Mohsin M Tak +2 more
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An unusual presentation of metastatic bone disease in a subject with Paget's disease of bone
Journal of Family Medicine and Primary Care, 2016 Solid organ malignancies involving breast, prostate, and lung frequently metastasize to the skeleton. However, the occurrence of Paget's disease and metastatic bone disease in the same patient is uncommon.
Shrinath Shetty +5 more
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Journal of Bone and Mineral Research, 1998 Abstract Paget's disease of bone is a localized disorder of bone remodeling. Increased numbers of larger than normal osteoclasts initiate the process at affected skeletal sites, and the increase in bone resorption is followed by an increase in new bone formation, altering bone architecture.
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BMC Health Services Research, 2008 Background Paget's disease of bone (PDB) disrupts normal bone architecture and causes pain, deformity, deafness, osteoarthritis, and fractures. Genetic factors play a role in PDB and genetic tests are now conducted for research purposes.
McCallum Marilyn +12 more
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Bone Marrow Cell Recognition: Training Deep Object Detection with A New Loss Function [PDF]
arXiv, 2021 For a long time, bone marrow cell morphology examination has been an essential tool for diagnosing blood diseases. However, it is still mainly dependent on the subjective diagnosis of experienced doctors, and there is no objective quantitative standard.
arxiv
Multiscale modeling of cancellous bone considering full coupling of mechanical, electrical and magnetic effects [PDF]
arXiv, 2021 Modeling of cancellous bone has important applications in the detection and treatment of fatigue fractures and diseases like osteoporosis. In this paper, we present a fully coupled multiscale approach considering mechanical, electrical and magnetic effects by using the multiscale finite element method and a two-phase material model on the microscale ...
arxiv
QJM, 2014 Paget's disease is an osteoclastic-mediated disorder of bone that results in abnormal bone resorption associated with inadequate remodeling that leads to mechanically weakened bone. Demonstrating variable geographic prevalence, it is becoming less frequent and age of onset is lengthening in areas of once high prevalence prior to the institution of ...
Pauline M. Camacho, Gregory Gruener
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