Results 71 to 80 of about 69,700 (263)

The Degradation of Access‐Based Business Models: Customer Misbehavior and Shared Mobility

Business Strategy and the Environment, EarlyView.
ABSTRACT Access‐based services are considered one of the strategies to embed sustainability in business models. Yet, because the evolution of these business models has been overlooked, we do not know whether their promise to create triple value is sustained.
Andres Camacho, Carmen Valor
wiley   +1 more source

Integrating Theory and Practice in Regenerative Supply Chain Management: An Integrative Review and Use‐Case Synthesis

Business Strategy and the Environment, EarlyView.
ABSTRACT This integrative review explores the evolution of sustainability in supply chain management and positions regenerative supply chain within the strong sustainability paradigm. It adopts a transdisciplinary approach, unfolding in two parallel stages.
Abhijeet Tewary, Ratri Parida, Surajit Bag   +2 more
wiley   +1 more source

Functional Stability of Plasminogen Activator Inhibitor-1

The Scientific World Journal, 2014
Plasminogen activator inhibitor-1 (PAI-1) is the main inhibitor of plasminogen activators, such as tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA), and a major regulator of the fibrinolytic system.
Songul Yasar Yildiz, Pinar Kuru, Ebru Toksoy Oner, Mehmet Agirbasli   +3 more
doaj   +1 more source

PAI-1 and TGF-β [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2006
Atherosclerosis is an extremely complex disease process in which genetic, lipid, cellular, and immunologic factors combine to determine the location, severity, and timing of lesion development and clinical events.1 With the current epidemic of obesity and the metabolic syndrome, additional factors are now recognized as contributors to the vascular ...
openaire   +1 more source

Climate Adequacy and Market Risk: Are They Related? Empirical Evidence From the European Equity Market Before and After the Adoption of the Paris Agreement

Business Strategy and the Environment, EarlyView.
ABSTRACT ESG ratings, and in particular environmental scores (E‐scores), are becoming increasingly relevant for financial stability and capital allocation decisions. This paper investigates the relationship between corporate environmental performance and market risk, as measured through value at risk (VaR) and expected shortfall (ES), the key metrics ...
Matilda Shini, Igor Gianfrancesco, Antonia Patrizia Iannuzzi, Vittorio Dell'Atti   +3 more
wiley   +1 more source

Innovation in the Face of Necessity: A Mixed‐Method Study of Student's Experience From an Anatomy Education Program Focused on a Near‐Peer Tutoring Module

Clinical Anatomy, EarlyView.
ABSTRACT Following institutional changes that reduced access to cadaveric dissection, Paris‐Saclay University developed a two‐year elective anatomy pathway serving as a longitudinal progression toward near‐peer tutoring (NPT). Designed as a complement to the core curriculum, the program preserves engagement with human dissection while promoting ...
Maud Creze, Thomas Bessede, Florian Petit Lemaire, Olga Avilova, Fabrice Duparc, Sanjib Kumar Ghosh   +5 more
wiley   +1 more source

FFNT25 ameliorates unilateral ureteral obstruction-induced renal fibrosis

Renal Failure, 2019
Renal fibrosis is a common pathological feature of chronic kidney disease (CKD) patients who progress to end-stage renal disease (ESRD). With the increasing incidence of CKD, it is of importance to develop effective therapies that blunt development of ...
Wen Li, Yue Lu, Yan Lou, Shiyue Zhao, Wenpeng Cui, Yangwei Wang, Manyu Luo, Jing Sun, Lining Miao   +8 more
doaj   +1 more source

Evaluating the Impact of a Dedicated Dissection Course on 3‐D Anatomical Understanding in Senior Medical Students

Clinical Anatomy, EarlyView.
ABSTRACT International changes in the focus of medical school education have led to a decrease in the time allocated to anatomy education, with human specimen dissection particularly affected. This study evaluates whether a dissection‐based course facilitates the retention of three‐dimensional (3‐D) anatomical relationships in senior medical students ...
Thomas Stubley, James Wooding, Janice Marshall, Robert S. Stephenson, Karuna Katti   +4 more
wiley   +1 more source

Plasminogen Activation Inhibitor-1 Promotes Resilience to Acute Oxidative Stress in Cerebral Arteries from Females

Pharmaceuticals
Plasminogen activation inhibitor-1 (PAI-1) plays a central role in thrombus formation leading to stroke; however, the contributions of PAI-1 to cellular damage in response to reactive oxygen species which are elevated during reperfusion are unknown ...
Safa, Charles E. Norton
doaj   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source