Results 61 to 70 of about 136,040,587 (306)

Precision targeting of the plasminogen activator inhibitor‐1 mechanism increases efficacy of fibrinolytic therapy in empyema

open access: yesPhysiological Reports, 2021
Plasminogen activator inhibitor‐1 (PAI‐1) is an endogenous irreversible inhibitor of tissue‐type (tPA) and urokinase (uPA) plasminogen activators. PAI‐1‐targeted fibrinolytic therapy (PAI‐1‐TFT) is designed to decrease the therapeutic dose of tPA and uPA,
Galina Florova   +12 more
doaj   +1 more source

TGFβ1-Induced PAI-1 Contributes to a Pro-Fibrotic Network in Eosinophilic Esophagitis

open access: yesJournal of Allergy and Clinical Immunology, 2016
Background Eosinophilic esophagitis is an allergic disease of increasing worldwide incidence. Complications are due to tissue remodeling and involve transforming growth factor-β1 (TGFβ1) mediated fibrosis.
R. Rawson   +9 more
semanticscholar   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

open access: yesAdvanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk   +6 more
wiley   +1 more source

PELAYANAN AKADEMIK DALAM MENINGKATKAN HASIL BELAJAR PAI SISWA DI SMA NEGERI 1 SOSORGADONG [PDF]

open access: yes, 2022
Penelitian ini bertujuan untuk menganalisa pelayanan akademik dalam meningkatkan hasil belajar PAI siswa di SMA Negeri 1 Sosorgadong. Fokus pembahasan dalam penelitian ini adalah implikasi pelayanan akademik tersebut pada hasil belajar siswa.
Pasaribu, Nurliani; SMA Negeri 1 Sosorgadong
core   +1 more source

Plasmon‐Enhanced Second‐Harmonic Generation in Atomically Thin Crystalline Silver Nanostructures

open access: yesAdvanced Materials, EarlyView.
Atomically thin crystalline silver films combine vertical quantum confinement with lateral plasmonic field enhancement to boost second‐harmonic generation. Nanoribbon and nanotriangle arrays enable geometry‐tunable infrared plasmon resonances, producing strong SHG from deeply subwavelength metallic volumes compatible with silicon‐based nanophotonics ...
Saad Abdullah   +10 more
wiley   +1 more source

STRATEGI GURU PAI DALAM MENINGKATKANPEMBELAJARAN PAI DIMASA PANDEMI DI SDN 1NUNGGAL REJO

open access: yes, 2022
ABSTRAKSTRATEGI GURU PAI DALAM MENGATASI PEMBELAJARAN PAI DIMASA PANDEMI DI SDN 1 NUNGGAL REJOOleh :CITRA AYU ANAGGRAININPM: 181210044Masa pandemi saat ini proses pembelajaran menjadi terganggu.
CITRA AYU ANGGRAINI NPM: 181210044 Prodi : Pendidikan Agama Islam (PAI)
core  

Bevacizumab promotes venous thromboembolism through the induction of PAI-1 in a mouse xenograft model of human lung carcinoma

open access: yesMolecular Cancer, 2015
BackgroundAn increased incidence of venous thromboembolism (VTE) is associated with anti-vascular endothelial growth factor (VEGF) treatment in cancer. However, the mechanism underlying this effect remains elusive.
Ni Chen   +11 more
semanticscholar   +1 more source

Efficient in‐Plane Exciton Transport in a Discontinuous Layered Lead‐Bromide Perovskite

open access: yesAdvanced Materials, EarlyView.
A new class of two‐dimensional lead‐bromide perovskite based on monovalent 4‐aminomethylbenzoic acid cations is presented, featuring a discontinuous inorganic layer. Despite the discontinuous lattice, transient photoluminescence microscopy demonstrates efficient though strongly anisotropic in‐plane exciton transport.
Raquel Utrera‐Melero   +9 more
wiley   +1 more source

Prevalence and Multiplicity of Thrombophilia Genetic Polymorphisms of FV, MTHFR, FII, and PAI-I: A Cross-Sectional Study on a Healthy Jordanian Population

open access: yesInternational Journal of General Medicine, 2021
Nabil Al-Zoubi,1 Nasr Alrabadi,2 Khalid Kheirallah,3 Ahmad Alqudah4 1Department of General Surgery/Vascular Surgery, Jordan University of Science and Technology, Irbid, 22110, Jordan; 2Department of Pharmacology, Faculty of Medicine, Jordan University of
Al-Zoubi N   +3 more
doaj  

A non-lethal traumatic/hemorrhagic insult strongly modulates the compartment-specific PAI-1 response in the subsequent polymicrobial sepsis.

open access: yesPLoS ONE, 2013
IntroductionPlasminogen activator inhibitor 1 (PAI-1) is a key factor in trauma- and sepsis-induced coagulopathy. We examined how trauma-hemorrhage (TH) modulates PAI-1 responses in subsequent cecal ligation and puncture (CLP)-induced sepsis, and the ...
Pierre Raeven   +7 more
doaj   +1 more source

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