Results 61 to 70 of about 405,913 (321)

‘It's not magic’: A qualitative analysis of geriatric physicians' explanations of cardio‐pulmonary resuscitation in hospital admissions

Health Expectations, 2021
Background Discussing patient preferences for cardio‐pulmonary resuscitation (CPR) is routine in hospital admission for older people. The way the conversation is conducted plays an important role for patient comprehension and the ethics of decision ...
Anca‐Cristina Sterie, Laura Jones, Ralf J. Jox, Eve Rubli Truchard   +3 more
doaj   +1 more source

Does the use of specialist palliative care services modify the effect of socioeconomic status on place of death? A systematic review [PDF]

, 2015
© SAGE Publications. Background: Cancer patients in lower socioeconomic groups are significantly less likely to die at home and experience more barriers to access to palliative care.
Allgar, Victoria, Chen, Hong, Dalgliesh, Christopher, Johnson, Miriam, MacLeod, Una, Nicolson, Donald J.   +5 more
core   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Nursing informatics competency and its associated factors among palliative care nurses: an online survey in mainland China

BMC Nursing
Background Nursing informatics (NI) competency is a required core competency for high-quality care in digitally enabled healthcare environments. Given the increasing reliance on digital health in palliative care settings, it becomes crucial to evaluate ...
Junchen Guo, Junqingzhao Liu, Chaoyi Liu, Ying Wang, Xianghua Xu, Yongyi Chen   +5 more
doaj   +1 more source

Characteristic of Paddle Squeezing Angle and AMBU Bag Air Volume in Bag Valve Mask Ventilator [PDF]

arXiv, 2021
In the COVID-19 period, the number of deaths has increased every day around the world. The pandemic has impacted the life and economy. Especially, there is a shortage in medical including a lack of technology, facility and equipment. One of those, ventilators are the essential equipment that does not provide enough requirements for the hospital.
arxiv  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Experiences of a Novel Integrated Service for Older Adults at Risk of Frailty: A Qualitative Study

Journal of Patient Experience, 2023
The UK has a significant and growing population of older adults with frailty and complex healthcare needs, necessitating innovative care solutions. This study aimed to explore patients’ and carers’ experiences of a novel integrated service that was set ...
Imogen Wilson MSc, Blessing O Ukoha-kalu PhD, Mabel Okoeki PhD, Joseph Clark PhD, Jason W Boland PhD, Sophie Pask MSc, Ugochinyere Nwulu MSc, Helene Elliott-Button PhD, Anna Folwell MBChB, Miriam J Johnson MD, Daniel Harman MBChB, Fliss EM Murtagh PhD   +11 more
doaj   +1 more source

Funding models in palliative care: lessons from international experience [PDF]

, 2017
Background:Funding models influence provision and development of palliative care services. As palliative care integrates into mainstream health care provision, opportunities to develop funding mechanisms arise.
Allan, Simon, Bausewein, Claudia, Cassel, J Brian, Cassel, J. Brian, Csikos, Agnes, Csikós, Ágnes, Eychmueller, Steffen, Furst, Carl Johan, Fürst, Carl Johan, García-Baquero Merino, Teresa, Groeneveld, E Iris, Groeneveld, E. Iris, Hasselaar, Jeroen, Haugen, Dagny Faksvag, Haugen, Dagny Faksvåg, Keller, Heike Gudat, Krajnik, Malgorzata, Merino, Teresa Garcia-Baquero, Merino, Teresa García Baquero, Murtagh, Fliss E. M., Murtagh, Fliss E.M., Murtagh, Fliss EM, Piper, Kym, Ryan, Karen, Swetenham, Kate, Swetenhaml, Kate   +25 more
core   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Perspectives of telemedicine-based services among family caregivers of patients with end-of-life cancer: a qualitative study in mainland China

BMC Palliative Care
Background Despite being driven by a strong sense of duty and familial obligation, providing care for patients nearing the end of life poses challenges for family caregivers.
Junchen Guo, Xianghua Xu, Chaoyi Liu, Ying Wang, Yongyi Chen   +4 more
doaj   +1 more source