Results 131 to 140 of about 2,409 (171)
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Biosynthesis of palmatine in Fagara coco
Phytochemistry, 1971Abstract The administration of sodium formate- 14 C to Fagara coco yielded, among other alkaloids, radioactive palmatine (I). Degradation of I clearly showed that almost 20% of the tracer was located on the berberine bridge carbon.
A.R. Skerl, E.G. Gros
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Studies on the interaction of palmatine hydrochloride with bovine hemoglobin
Luminescence, 2013ABSTRACTThe interaction between bovine hemoglobin (BHb) and palmatine hydrochloride (PMT) was investigated at different temperatures using multispectroscopy, as well as the effect of common metal ions (Ca2+, Mg2+, Zn2+, Cu2+, Fe2+, Fe3+, Co2+, Ni2+) on the BHb–PMT system.
Baosheng, Liu +4 more
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Journal of Molecular Structure, 2021
Abstract In order to improve the hygroscopic stability of palmatine chloride (PMTCl) without reducing its solubility, on the basis of summarizing tetrahydroberberine and sulfophenyl acids pharmaceutical cocrystals/salts, we speculated that sodium saccharinate (SACNa), an organic acid salt with the same sulfonyl group, may be cocrystallized with ionic
Yunan Zhang +11 more
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Abstract In order to improve the hygroscopic stability of palmatine chloride (PMTCl) without reducing its solubility, on the basis of summarizing tetrahydroberberine and sulfophenyl acids pharmaceutical cocrystals/salts, we speculated that sodium saccharinate (SACNa), an organic acid salt with the same sulfonyl group, may be cocrystallized with ionic
Yunan Zhang +11 more
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Identification of palmatine as an inhibitor of West Nile virus
Archives of Virology, 2010In this study, we investigated the specific inhibition of West Nile virus (WNV) NS2B-NS3 protease and viral propagation by palmatine, a chemical compound from Coptis chinensis Franch. It was demonstrated that palmatine could inhibit WNV NS2B-NS3 protease activity in an uncompetitive manner, with a 50% inhibitory concentration (IC(50)) of 96 microM ...
Fan, Jia +3 more
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Fluorescence enhancement method for palmatine extraction by SWMONTs
Journal of Coordination Chemistry, 2020Single-walled metal-organic nanotubes (SWMONTs) could be dried in vacuum to obtain SWMONTs with activation sites.
Linyan Yang +5 more
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Radiolysis of berberine or palmatine in aqueous solution
Radiation Physics and Chemistry, 2011The reactions of hydrated electron (eaq−), hydrogen atom (H) (reducing species) and Cl2•−,Br2•−,N•3,O•H radicals (oxidizing species) with berberine or palmatine in aqueous solution have been studied by steady-state and pulse radiolysis. The spectra of transient intermediates, leading to the final products, are presented.
Milena Marszalek, Marian Wolszczak
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Journal of Drug Delivery Science and Technology, 2021
Abstract In order to ameliorate the hygroscopicity of palmatine chloride (PMTCl), an unreported salt cocrystal (2(C21H22O4NCl)·C7H6O5·2CH3OH, PMTCl-GA) of palmatine chloride with gallic acid (GA) has been designed and synthesized by a solvent evaporation method.
Yu-nan Zhang +7 more
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Abstract In order to ameliorate the hygroscopicity of palmatine chloride (PMTCl), an unreported salt cocrystal (2(C21H22O4NCl)·C7H6O5·2CH3OH, PMTCl-GA) of palmatine chloride with gallic acid (GA) has been designed and synthesized by a solvent evaporation method.
Yu-nan Zhang +7 more
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Predominant Binding Mode of Palmatine to DNA
The Journal of Physical Chemistry LettersPalmatine is a protoberberine alkaloid, which may produce singlet oxygen under visible light irradiation and binds to DNA. The fact that singlet oxygen activation in palmatine may be triggered by environmental conditions, and in particular its interaction with nucleic acids, makes it a most suitable candidate for photodynamic therapy and DNA-targeted ...
Marziogiuseppe Gentile +4 more
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A biogenetically patterned conversion of palmatine into polycarpine
Tetrahedron Letters, 1979Abstract Oxidation of palmatine ( 1 ) choride with m -chloroperbenzoic acid in methylene chloride in the presence of sodium bicarbonate at near −78° C yields polycarpine ( 2 ). A new biogenetic route to the aporphines is proposed which does not involve phenolic oxidative coupling, and proceeds through the intermediacy of protoberberinium
Natesan Murugesan, Maurice Shamma
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Palmatine ameliorates nephrotoxicity and hepatotoxicity induced by gentamicin in rats
Archives of Physiology and Biochemistry, 2019The aim of this study was to investigate the effects of palmatine on gentamicin toxicity. Rats arranged in four groups: 1- Sham, 2- GM, 3- & 4- GM + palmatine (50 & 100 mg/kg). Gentamicin led to increase in plasma AST, ALT, BUN and creatinine. In addition, fractional excretion of Na and K were increased and urine flow rate and creatinine clearance were
Mehdi Khaksari +3 more
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