Results 161 to 170 of about 126,289 (311)

Development of NAFLD‐Specific Human Liver Organoid Models on a Microengineered Array Chip for Semaglutide Efficacy Evaluation

Cell Proliferation, EarlyView.
Microporous array organ chips were integrated with commercially available well plates to develop organoid chip platforms, which enable modelling of hepatic physiology and non‐alcoholic fatty liver disease (NAFLD) pathogenesis, as well as evaluation of semaglutide therapeutics. ABSTRACT Progressive non‐alcoholic fatty liver disease (NAFLD) may culminate
Xiao‐yan You, Xiang‐yang Li, Hui Wang, Guo‐ping Zhao   +3 more
wiley   +1 more source

U.S. Biodiesel Development: New Markets for Conventional and Genetically Modified Agricultural Products [PDF]

With environmental and energy source concerns on the rise, using agricultural fats and oils as fuel in diesel engines has captured increasing attention.
Duffield, James A., Graboski, Michael S., McCormick, Robert, Shapouri, Hosein, Wilson, Richard   +4 more
core   +1 more source

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

Cell Proliferation, EarlyView.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo, Zexin Yang, Junsen She, Chen Fang, Yizhi Hu, Hefeng Huang, Ling Gao   +6 more
wiley   +1 more source

Multiple Roles of Palmitic Acid in Cardiovascular Diseases. [PDF]

J Inflamm Res
Jiang H, Na C, Zhu Y, Bi Y, Yang R, Yang R, Yang H, Niu M, Huang X, Yang J.   +9 more
europepmc   +1 more source

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

Dietary palmitic acid inhibits colorectal cancer progression through enhancing bisecting GlcNAc. [PDF]

JCI Insight
Lei L, Tang J, Lv Y, Jia B, Cai W, Sheng S, Li K, Shi Z, Fan N, Tan Z, Li X, Guan F.   +11 more
europepmc   +1 more source

Is AMP‐activated protein kinase activation a central mechanism of cardio‐metabolic outcomes after metabolic and bariatric surgery?

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity. It usually results in spectacular weight loss, associated with improvements of obesity‐associated comorbidities. The mechanisms underlying these benefits are not fully understood but could involve a postoperative activation of the enzyme 5′ AMP‐activated ...
Adrien Delcour, Nathalie Niederhoffer
wiley   +1 more source

Palmitic acid-triggered B7H3 palmitoylation promotes immune escape. [PDF]

Nat Commun
Rao Z, Huang C, Wu Q, Li M, Liu A, Zhu T, Yang W, Yin L, Zhu S, She X, Yu C, Liu L, Li P, Bai Y, Zhang D, Xie T, Liu X, Liu L, Xu F, Wang G, Hu J, Luo X.   +21 more
europepmc   +1 more source

Multiparasitism Resolves the Apparent Paradox of High Male Pheromone Investment Despite Frequent Within‐Host Mating in a Parasitoid

Entomologia Experimentalis et Applicata, EarlyView.
It is unknown why males of the parasitoid wasp Nasonia giraulti produce large amounts of a costly sex pheromone although they were long thought to mate with their females already before emergence within the host. Mated females do no longer respond to the pheromone.
Martina Wendler, Verena Engl, Joachim Ruther   +2 more
wiley   +1 more source

Dose-Dependent Biphasic Effect of Palmitic Acid on Oligodendrocyte Function: Impacts on Viability, Differentiation, and Myelination. [PDF]

J Cell Physiol
Palmiero A, Pipicelli L, Rosa G, Sozio C, Punziano C, Raia M, Faraonio R, Vitolo G, Cammarota M, Boscia F, Menale C, Santillo M, Damiano S.   +12 more
europepmc   +1 more source