Results 21 to 30 of about 62,902 (314)

Interaction of Palmitic Acid with Metoprolol Succinate at the Binding Sites of Bovine Serum Albumin [PDF]

Advanced Pharmaceutical Bulletin, 2014
Purpose: The aim of this study was to characterize the binding profile as well as to notify the interaction of palmitic acid with metoprolol succinate at its binding site on albumin.
Mashiur Rahman, Farzana Prianka, Mohammad Shohel, Md. Abdul Mazid   +3 more
doaj   +1 more source

Protective Effects of Linoleic Acid against the Cytotoxicity of Palmitic Fatty Acid in Rat Cardiomyocytes [PDF]

Journal of Kerman University of Medical Sciences, 2016
Background & Aims: Lipotoxicity is the process through which accumulation of lipid intermadiates leads to cellular dysfunction. The worldwide prevalence of cardiovascular diseases has been increased dramatically due to lipotoxicity.
Elham Zadeh Hashem, Freshteh Panahandeh, Behzad Lame- Rad   +2 more
doaj  

Toll-like receptor 4 is a master regulator for colorectal cancer growth under high-fat diet by programming cancer metabolism

Cell Death and Disease, 2021
Although high-fat diet (HFD) has been implicated in the development of colorectal cancer (CRC), the critical signaling molecule that mediates the cancer growth is not well-defined.
Xianjing Hu, Sarwat Fatima, Minting Chen, Keyang Xu, Chunhua Huang, Rui-Hong Gong, Tao Su, Hoi Leong Xavier Wong, Zhaoxiang Bian, Hiu Yee Kwan   +9 more
doaj   +1 more source

The Distinct Effects of Palmitic and Oleic Acid on Pancreatic Beta Cell Function: The Elucidation of Associated Mechanisms and Effector Molecules

Frontiers in Pharmacology, 2019
In this study, we aimed to identify the mechanisms underlying the different effects of palmitic acid and oleic acid on human pancreatic beta cell function.
Miruna Nemecz, Alina Constantin, Madalina Dumitrescu, Nicoleta Alexandru, Alexandru Filippi, Gabriela Tanko, Adriana Georgescu   +6 more
doaj   +1 more source

Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?

International Journal of Endocrinology, 2018
Our previous studies suggested that the thyroid might be a target organ affected by lipotoxicity, which might be partially related to the increasing prevalence of subclinical hypothyroidism.
Meng Zhao, Xiaohan Zhang, Ling Gao, Yongfeng Song, Chao Xu, Chunxiao Yu, Shanshan Shao, Jiajun Zhao   +7 more
doaj   +1 more source

Determination and correlation analysis of tobacco non-volatile organic acids and pH

Shipin yu jixie, 2022
Objective: To explore the effects of organic acids on tobacco pH and flue gas pH. Methods: 34 kinds of single-grade tobacco and 11 kinds of finished cigarettes were taken as the research objects, and their non-volatile organic acids, tobacco pH, and the ...
PIAO Yong-ge, ZHANG Jia-bao, CUI Cheng-zhe, LIU You-jie, LI He-lin, LI Rui-li, ZHANG Jun-song   +6 more
doaj   +1 more source

Role of palmitic acid on the isolation and properties of halorhodopsin

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1996
Purified halorhodopsin was isolated from Halobacterium halobium as previously described (Duschl, A. et al. (1988) J. Biol. Chem. 263, 17016-17022). Two purple bands were eluted from phenyl-Sepharose column, indicating the presence of differently retained halorhodopsin forms; the absorption spectra of the two halorhodopsin bands in the dark were not ...
A Corcelli, S Lobasso, M Colella, M Trotta, A Guerrieri, F Palmisano   +5 more
openaire   +6 more sources

A Mutant of Arabidopsis Deficient in the Elongation of Palmitic Acid [PDF]

Plant Physiology, 1994
The overall fatty acid composition of leaf lipids in a mutant of Arabidopsis thaliana was characterized by an increased level of 16:0 and a concomitant decrease of 18-carbon fatty acids as a consequence of a single recessive nuclear mutation at the fab1 locus.
D. James, John Browse, Jingrui Wu, H. K. Dooner   +3 more
openaire   +3 more sources

Palmitic Acid Induces Production of Proinflammatory Cytokines Interleukin-6, Interleukin-1β, and Tumor Necrosis Factor-α via a NF-κB-Dependent Mechanism in HaCaT Keratinocytes

Mediators of Inflammation, 2013
To investigate whether palmitic acid can be responsible for the induction of inflammatory processes, HaCaT keratinocytes were treated with palmitic acid at pathophysiologically relevant concentrations.
Bing-rong Zhou, Jia-an Zhang, Qian Zhang, Felicia Permatasari, Yang Xu, Di Wu, Zhi-qiang Yin, Dan Luo   +7 more
doaj   +1 more source

Chlorogenic acid against palmitic acid in endoplasmic reticulum stress-mediated apoptosis resulting in protective effect of primary rat hepatocytes

Lipids in Health and Disease, 2018
Background We demonstrated growing evidence supports a protective role of chlorogenic acid of rat hepatocytes elicited by two compounds, i.e. thapsigargin and palmitic acid.
Yong Zhang, Liangsheng Miao, Huijuan Zhang, Gang Wu, Zhenni Zhang, Jianrui Lv   +5 more
doaj   +1 more source