Results 1 to 10 of about 92,966 (245)
Palmitic acid: Enabling the tumor’s nerves
Diet can influence tumor aggressiveness. Recently in Nature, a study by Pascual et al. provided evidence that dietary palmitic acid induces an epigenetic memory by modulating particular histone methylation marks in cancer cells. This allows cancer cells to activate extracellular matrix secretion from Schwann cells of the tumor microenvironment, which ...
Alkan, H. Furkan+2 more
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Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12 [PDF]
Excessive saturated fatty acids have been considered to be one of major contributing factors for the dysfunction of skeletal muscle cells as well as pancreatic beta cells, leading to the pathogenesis of type 2 diabetes.PA induced cell death in a dose dependent manner up to 1.5 mM, but AA protected substantially lipotoxicity caused by PA at even low ...
Hyae Gyeong Cheon, Young Sik Cho
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Activation of Palmitic Acid by Human Spermatozoa [PDF]
Human spermatozoa were studied to determine if a long chain fatty acid, CoASH ligase (AMP) (E.C. 6.2.1.3), was present. Ligase activity was measured with a radioligand millipore filter technique and was readily detectable in spermatozoa or in the protein fraction extracted with Triton X‐100, but was not present in seminal plasma.
Robert E. Jones+2 more
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Calcium palmitate and -palmitic acid in gallstones [PDF]
Calcium palmitate occurred in 20% of the gallstones studied in this laboratory by x-ray diffraction and was the most important crystalline constituent after the different forms of cholesterol and calcium carbonate. Only one calculus contained alpha-palmitic acid.
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Impact of Dietary Palmitic Acid on Lipid Metabolism
Palmitic acid (PA) is ubiquitously present in dietary fat guaranteeing an average intake of about 20 g/d. The relative high requirement and relative content in the human body, which accounts for 20–30% of total fatty acids (FAs), is justified by its relevant nutritional role.
Murru E., Manca C., Carta G., Banni S.
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Ascorbyl-6-Palmitate is not Ascorbic Acid [PDF]
The skin protects itself from oxidative stress, generated by sunlight and pollution, with enzymic and nonenzymic antioxidants. The major nonenzymic antioxidants include L-ascorbic acid, glutathione, a-tocopherol, and ubiquinone/ubiquinol. Lascorbic acid protects the aqueous space and is the most plentiful antioxidant in skin.
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Relative utilization of free palmitic acid, glyceryl palmitate and ethyl palmitate by dogs [PDF]
Digestibility of fats depends on several factors which may be grouped as: (1) mechanical, e. g., melting point which determines the rate of gastric discharge1 and, to a considerable extent, the degree of emulsification; and (2) chemical which determines the character of the products of digestion and the rate of hydrolysis, certain esters of fatty acids,
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Role of palmitic acid on the isolation and properties of halorhodopsin
Purified halorhodopsin was isolated from Halobacterium halobium as previously described (Duschl, A. et al. (1988) J. Biol. Chem. 263, 17016-17022). Two purple bands were eluted from phenyl-Sepharose column, indicating the presence of differently retained halorhodopsin forms; the absorption spectra of the two halorhodopsin bands in the dark were not ...
A Corcelli+5 more
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A Mutant of Arabidopsis Deficient in the Elongation of Palmitic Acid [PDF]
The overall fatty acid composition of leaf lipids in a mutant of Arabidopsis thaliana was characterized by an increased level of 16:0 and a concomitant decrease of 18-carbon fatty acids as a consequence of a single recessive nuclear mutation at the fab1 locus.
D. James+3 more
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The aim of the present study was to develop nanotechnology-based oral formulations of glipizide to enhance the bioavailability and eliminate the frequent oral administration of the conventional dosage form. Glipizide is an antidiabetic drug with a short biological half-life and limited oral bioavailability.
Vipan Kumar KAMBOJ+1 more
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