Results 151 to 160 of about 92,966 (245)

ON THE CONVERSION OF PALMITIC ACID TO STEARIC ACID IN ANIMAL TISSUES

Journal of Biological Chemistry, 1951
openaire   +3 more sources

Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co‐Culture System

Cell Proliferation, EarlyView.
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai, Jiting Li, Ze Wang, Yuhan Yang, Jieqing He, Gonglie Chen, Yufan Zhang, Yan Qi, Zhongjun Wan, Lin Cai, Run Wang, Kai Wang, Dongyu Zhao, Jingzhong Zhang, Weihua Huang, Ronald X. Xu, Mingzhai Sun, Xiao Han, Yan Liu, Donghui Zhang, Wanying Zhu, Jian Liu, Yuxuan Guo   +22 more
wiley   +1 more source

A Novel Infant Formula with Medium- and Long-Chain Triacylglycerols and <i>sn</i>-2 Palmitate Supports Adequate Growth and Lipid Absorption in Healthy Term Infants. [PDF]

Nutrients
Chen X, Yang M, Wei W, Huang S, Qiu Y, Li Z, Lan Q, Huang B, Wu T, Bi Q, Wang X, Zhu H.   +11 more
europepmc   +1 more source

Long‐term fasting induces a remodelling of fatty acid composition in erythrocyte membranes

European Journal of Clinical Investigation, Volume 55, Issue 5, May 2025.
Abstract Introduction Long‐term fasting (LF) activates an adaptative response to switch metabolic fuels from food glucose to lipids stored in adipose tissues. The increase in free fatty acid (FFA) oxidation during fasting triggers health benefits. We questioned if the changes in lipid metabolism during LF could affect lipids in cell membranes in humans.
Katharina Gewecke, Franziska Grundler, Massimiliano Ruscica, Clemens von Schacky, Robin Mesnage, Françoise Wilhelmi de Toledo   +5 more
wiley   +1 more source

Global changes in <i>Staphylococcus aureus</i> virulence and metabolism during colonization of healthy skin. [PDF]

Infect Immun
Enroth TJ, Severn MM, Costa FG, Bovee AR, Wilkening RV, Nguyen DT, Langouët-Astrié C, Horswill AR.   +7 more
europepmc   +1 more source

Lipid regulation of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis by its membrane‐domain receptor

The FEBS Journal, EarlyView.
The adenylyl cyclase (AC) Rv1625c from M. tuberculosis is a monomeric progenitor of the nine pseudoheterodimeric mammalian AC isoforms. The hexahelical membrane anchor of Rv1625c serves as an inhibitory receptor for fatty acids, particularly oleic acid. One ligand binds into each monomer of the active Rv1625c dimer.
Anita Charlotte Friderun Schultz, Marius Landau, Andrei N. Lupas, Joachim Erdmann Schultz   +3 more
wiley   +1 more source

Uncovering the heterogeneity of the gut microbial taxa associated with the contents of different fatty acids in muscle with cecum luminal content and fecal samples from two pig populations. [PDF]

Front Microbiol
Sun X, Yang B, Chen C.
europepmc   +1 more source

Adipocyte exosome miR‐4472 inhibits glucose uptake in skeletal muscle through downregulation of MEF2D

Journal of Diabetes Investigation, EarlyView.
Adipocyte exosome miR‐4472 inhibits glucose uptake in skeletal muscle through downregulating the expression of MEF2D/GLUT4. ABSTRACT Aims/introduction Previous studies have found that miR‐4472 is overexpressed in the serum of individuals with obesity and type 2 diabetes mellitus (T2DM), which may participate in the process of obesity‐induced T2DM ...
Chaoyue Sun, Xin Wen, Xiaolong Chu, Fangyuan Yuan, Yao Chen, Chaoling Peng, Meiyu Qian, Jin Mei, Juan Wang, Yidan Jiang, Shibo Xu, Cuizhe Wang, Wei Li, Jun Zhang   +13 more
wiley   +1 more source

Identifying the metabolic profile of Hashimoto's thyroiditis from the METHAP clinical study. [PDF]

Sci Rep
Sarandi E, Tsoukalas D, Rudofsky G, Fragoulakis V, Liapi C, Paramera E, Papakonstantinou E, Krueger Krasagakis S, Tsatsakis A.   +8 more
europepmc   +1 more source

Uhrf1 downregulation promotes β‐cell dedifferentiation by decreasing Foxo1 expression in type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This finding reveals the important role of Uhrf1 in the β‐cell dedifferentiation of T2D, providing a potential target for its treatment. ABSTRACT Background Islet β‐cell dedifferentiation is a major pathological mechanism of type 2 diabetes (T2D). Forkhead box o1 (Foxo1) is a master regulator of β‐cell dedifferentiation.
Lanfang Fu, Juyun Zhang, Zhu Lin, Xubiao Meng   +3 more
wiley   +1 more source