Results 211 to 220 of about 110,039 (337)

Development of NAFLD‐Specific Human Liver Organoid Models on a Microengineered Array Chip for Semaglutide Efficacy Evaluation

open access: yesCell Proliferation, EarlyView.
Microporous array organ chips were integrated with commercially available well plates to develop organoid chip platforms, which enable modelling of hepatic physiology and non‐alcoholic fatty liver disease (NAFLD) pathogenesis, as well as evaluation of semaglutide therapeutics. ABSTRACT Progressive non‐alcoholic fatty liver disease (NAFLD) may culminate
Xiao‐yan You   +3 more
wiley   +1 more source

Multiple Roles of Palmitic Acid in Cardiovascular Diseases. [PDF]

open access: yesJ Inflamm Res
Jiang H   +9 more
europepmc   +1 more source

The differential effects of palmitic acid and oleic acid on the metabolic response of hypothalamic astrocytes from male and female mice [PDF]

open access: bronze
Roberto Collado‐Perez   +8 more
openalex   +1 more source

In silico; Linoleic acid and palmitic acid exerts antidiabetic effects by inhibiting protein tyrosine phosphatases associated with insulin resistance

open access: gold, 2023
Maha Hameed Al-bahrani   +93 more
openalex   +2 more sources

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

open access: yesCell Proliferation, EarlyView.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo   +6 more
wiley   +1 more source

Improvement of Cottonseed Oil and Fatty Acids Through Introgression Breeding in Upland Cotton. [PDF]

open access: yesPlants (Basel)
Kandel S   +7 more
europepmc   +1 more source

Unveiling the Crucial Nexus: Mitochondrial Quality Control as a Central Driver in Metabolic Dysfunction‐Associated Steatotic Liver Disease Pathogenesis

open access: yesCell Proliferation, EarlyView.
Mitochondrial quality control (MQC) impairment plays a central role in driving the pathogenesis of metabolism‐associated steatotic liver disease (MASLD). Specifically, this is manifested as reduced mitophagy; increased mitochondrial fission and decreased fusion; and impaired mitochondrial biogenesis.
Wenkai Fu   +8 more
wiley   +1 more source

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