Results 291 to 300 of about 110,039 (337)

A Digital Phantom for MR Spectroscopy Data Simulation

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 3, Page 1345-1359, March 2026.
ABSTRACT Purpose Simulated data is increasingly valued by researchers for validating MRS processing and analysis algorithms. However, there is no consensus on the optimal approaches for simulation models and parameters. This study introduces a novel MRS digital brain phantom framework, providing a comprehensive and modular foundation for MRS data ...
D. M. J. van de Sande   +11 more
wiley   +1 more source

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

open access: yesTraffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang   +7 more
wiley   +1 more source

Fatty Acids Analysis of Four Pistacia Species by Gas Chromatography Coupled With Mass Spectrometry via Multivariate Chemometrics. [PDF]

open access: yesChem Biodivers
Boukelouaa A   +7 more
europepmc   +1 more source

Adipocyte fatty acid‐binding protein as a cerebrospinal fluid–accessible biomarker and druggable target in subarachnoid haemorrhage: Linking fatty acid dysregulation to microglial neuroinflammation

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
A‐FABP mediates neuroinflammation and exaggerates SAH outcomes: In response to SAH, elevated A‐FABP combines with fatty acids to promote microglia activation via the JAK2/STAT3 pathway, while simultaneously disrupting fatty acid metabolism. These dual effects exacerbate neuroinflammation and neurological deterioration, thereby contributing to adverse ...
Xingwu Liu   +13 more
wiley   +1 more source

The role of protein S-acylation in vascular injury associated with metabolic disorders. [PDF]

open access: yesFront Endocrinol (Lausanne)
Wang Y   +8 more
europepmc   +1 more source

Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2‐nitroimidazole TAT Conjugate

open access: yesDrug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Mediated by their protein transduction domain, cell‐penetrating peptides (CPPs) have been widely explored for facilitating intracellular delivery of drugs and small molecules. In this study, a radiolabeled, 2‐nitroimidazole conjugated TAT (TAT ‐ transactivator of transcription) peptide was prepared and evaluated for targeting tumor hypoxia ...
Sweety Mittal   +4 more
wiley   +1 more source

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