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Palmitic acid: Enabling the tumor’s nerves

Cell Metabolism, 2022
Diet can influence tumor aggressiveness. Recently in Nature, a study by Pascual et al. provided evidence that dietary palmitic acid induces an epigenetic memory by modulating particular histone methylation marks in cancer cells. This allows cancer cells to activate extracellular matrix secretion from Schwann cells of the tumor microenvironment, which ...
H Furkan, Alkan   +2 more
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Palmitic Acid and Health: Introduction

Critical Reviews in Food Science and Nutrition, 2015
Interest in the dietary role and metabolic effect of saturated fatty acids has been recently renewed on the basis of epidemiologic observations and economical approach to health and well-being. Saturated fats may favorably increase blood HDL-Cholesterol levels without significant changes of the total cholesterol/HDL-Cholesterol ratio.
C. Agostoni, L. Moreno, R. Shamir
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The effect of palmitic acid on lipoprotein cholesterol levels

International Journal of Food Sciences and Nutrition, 2000
The present study assessed the effect of high versus low palmitic acid intakes of plasma lipoprotein cholesterol levels and on rates for endogenous synthesis of cholesterol in normal and hypercholesterolemic subjects. On day 21 of each diet treatment, a fasting blood sample was drawn for lipoprotein determination and to provide a measure of the ...
Michael T. Clandinin   +3 more
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Biosynthesis of 15,16-dimethyltriacontanedioic acid (diabolic acid) from [16-2H3]- and [14-2H2]-palmitic acids

, 1992
It is shown that no loss of deuterium occurs during formation of 15, 16-dimethyltriacontanedioic acid (diabolic acid) from [16-2H3]palmitic acid and [14-2H2]palmitic acid in Butyrivibrio fibrisolvens.
W. Fitz, D. Arigoni
semanticscholar   +1 more source

Metabolism of palmitic acid in perfused rat heart

American Journal of Physiology-Legacy Content, 1963
Metabolism of fatty acid was studied in the isolated rat heart perfused with albumin-bound palmitate-C14. Uptake of fatty acid by the heart was related to the concentration of fatty acid present and the molar ratio of fatty acid to albumin in the perfusion fluid. Disappearance of lipid-bound radioactivity from the perfusion fluid (palmitate-C14 uptake)
John R. Evans   +2 more
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Effects of palmitate on astrocyte amino acid contents

Neurochemical Research, 1989
The effects of palmitate on intracellular and extracellular amino acid concentrations of cultured astrocytes was studied. Exposure of astrocytes to either 0.72 mM or 0.36 mM palmitate was associated with a significant reduction in the intracellular pool of glutamine and taurine.
M, Yudkoff   +4 more
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Esterification of palmitic acid in swine aortic microsomes

Biochemical Medicine, 1978
Abstract The incorporation of labeled palmitic acid into lipids was studied in swine aortic microsomes. The results showed that palmitic acid was actively incorporated into phospholipids and neutral lipids. Low fatty acid esterification was observed when cofactors (ATP, CoA, Mg 2+ , and F − ) were omitted from incubation medium.
William Y. Huang, Fred A. Kummerow
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Zeolite catalyzed palmitic acid esterification

Microporous and Mesoporous Materials, 2018
Abstract The present study compares four commercial H-Y and ZSM-5 zeolites as solid acid catalysts for the conversion of palmitic acid to methyl palmitate under smooth conditions. The palmitic acid conversion did not show a clear correlation with the amount of acid sites on the catalysts surface and depended more on the porosity and the hydrophobic ...
Pepijn Prinsen   +2 more
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Esterification of palmitic acid in swine aortic homogenates

Lipids, 1978
AbstractThe incorporation of [1‐14C] palmitic acid into tissue lipids of the medial and intimal layers of swine aortic homogenates was investigated. The homogenates obtained were metabolically active as indicated by their ready incorporation of labeled palmitic acid into phospholipids, diglycerides and triglycerides in the presence of α ...
Fred A. Kumerow, William Y. Huang
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Palmitic Acid Kinetics in Fasting, Traumatized Patients

The Journal of Trauma: Injury, Infection, and Critical Care, 1992
The contribution of free fatty acid oxidation to the elevation in energy expenditure after trauma has not been well characterized. Six control subjects and six traumatized patients were fasted for 48 hours and given a primed continuous infusion of (1-14C)palmitate to measure plasma palmitate and total free fatty acid kinetics.
Robert J. Cardwell   +5 more
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