Results 31 to 40 of about 5,059,827 (335)

Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress. [PDF]

open access: yesPLoS ONE, 2015
Lipotoxicity plays an important role in pancreatic β-cell failure during the development of type 2 diabetes. Prolonged exposure of β-cells to elevated free fatty acids level could cause deterioration of β-cell function and induce cell apoptosis ...
Yuren Zhou   +5 more
doaj   +1 more source

Anaerobic biodegradation of oleic and palmitic acids: evidence of mass transfer limitations caused by long chain fatty acid accumulation onto the anaerobic sludge.

open access: yesBiotechnology and Bioengineering, 2005
Palmitic acid was the main long chain fatty acids (LCFA) that accumulated onto the anaerobic sludge when oleic acid was fed to an EGSB reactor. The conversion between oleic and palmitic acid was linked to the biological activity.
M. Pereira   +3 more
semanticscholar   +1 more source

Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis

open access: yesNutrition and Metabolism, 2020
Background Pyroptosis is a novel programmed cell death. It is identified as caspase-1 dependent and characterized by plasma-membrane rupture and release of proinflammatory intracellular contents inculuding IL-1 beta and IL-18. Pyroptosis is distinct from
Xin Zeng   +9 more
semanticscholar   +1 more source

CRISPR/Cas9-Mediated Knockout of GmFATB1 Significantly Reduced the Amount of Saturated Fatty Acids in Soybean Seeds

open access: yesInternational Journal of Molecular Sciences, 2021
Soybean (Glycine max) oil is one of the most widely used vegetable oils across the world. Breeding of soybean to reduce the saturated fatty acid (FA) content, which is linked to cardiovascular disease, would be of great significance for nutritional ...
Jing Ma, Shuo Sun, J. Whelan, H. Shou
semanticscholar   +1 more source

Desaturation and interconversion of dietary stearic and palmitic acids in human plasma and lipoproteins.

open access: yesAmerican Journal of Clinical Nutrition, 1997
Dietary saturated fatty acids are implicated as a risk factor for atherosclerosis. The conversion of the major dietary saturated fatty acids stearic acid (18:0) and palmitic acid (16:0) to monounsaturated fatty acids in whole plasma and lipoprotein ...
Sue K Rhee   +3 more
semanticscholar   +1 more source

Role of palmitic acid on the isolation and properties of halorhodopsin

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1996
Purified halorhodopsin was isolated from Halobacterium halobium as previously described (Duschl, A. et al. (1988) J. Biol. Chem. 263, 17016-17022). Two purple bands were eluted from phenyl-Sepharose column, indicating the presence of differently retained halorhodopsin forms; the absorption spectra of the two halorhodopsin bands in the dark were not ...
A Corcelli   +5 more
openaire   +6 more sources

A Mutant of Arabidopsis Deficient in the Elongation of Palmitic Acid [PDF]

open access: yesPlant Physiology, 1994
The overall fatty acid composition of leaf lipids in a mutant of Arabidopsis thaliana was characterized by an increased level of 16:0 and a concomitant decrease of 18-carbon fatty acids as a consequence of a single recessive nuclear mutation at the fab1 locus.
D. James   +3 more
openaire   +3 more sources

Bioactive Compounds in Sarcocornia and Arthrocnemum, Two Wild Halophilic Genera from the Iberian Peninsula

open access: yesPlants, 2021
(1) Background: this study describes bioactive compounds in the following halophytes: Sarcocornia (S. alpini, S. pruinosa, and S. perennis) and Arthrocnemum (A. macrostachyum).
Irene Sánchez-Gavilán   +2 more
doaj   +1 more source

The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders

open access: yesBiomolecules, 2020
This review presents existing evidence of the influence of saturated and unsaturated fatty acids on cardiovascular diseases (CVD). Data are discussed regarding the roles of the most relevant fatty acids, such as myristic (C14:0), palmitic (C16:0 ...
V. Shramko   +4 more
semanticscholar   +1 more source

Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski   +3 more
wiley   +1 more source

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