Results 41 to 50 of about 5,059,827 (335)
Advanced Materials, EarlyView.Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash +9 more
wiley +1 more source
The Turkish Journal of Pharmaceutical Sciences, 2018 The aim of the present study was to develop nanotechnology-based oral formulations of glipizide to enhance the bioavailability and eliminate the frequent oral administration of the conventional dosage form. Glipizide is an antidiabetic drug with a short biological half-life and limited oral bioavailability.
Vipan Kumar KAMBOJ +1 more
openaire +2 more sources
Advanced Synthesis &Catalysis, EarlyView.The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley +1 more source
Caveolar fatty acids and acylation of caveolin-1. [PDF]
PLoS ONE, 2013 Caveolae are cholesterol and sphingolipids rich subcellular domains on plasma membrane. Caveolae contain a variety of signaling proteins which provide platforms for signaling transduction.
Qian Cai +3 more
doaj +1 more source
Nutrients, 2020 Fats that are rich in palmitic or stearic acids can be interesterified to increase their applicability for the production of certain foods. When compared with palmitic acid, stearic acid lowers low-density lipoprotein (LDL)-cholesterol, which is a well ...
M. V. van Rooijen, R. Mensink
semanticscholar +1 more source
Advanced Science, EarlyView.This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu +13 more
wiley +1 more source
Effect of α-Bromo-palmitate on the Oxidation of Palmitic Acid by Rat Liver Cells
Journal of Biological Chemistry, 1971 Abstract Rat liver cell suspensions oxidized [1-14C]palmitic acid and [1-14C]palmitoyl-l-carnitine efficiently to CO2. Oxidation of tracer amounts of palmitate was inhibited by α-bromo-palmitate (2 x 10-4 m). The oxidation of tracer amounts of palmitoyl-l-carnitine was not affected.
F. D. Sauer, S. Mahadevan
openaire +3 more sources
Post‐Translational Modifications in Cilia and Ciliopathies
Advanced Science, EarlyView.This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley +1 more source
Journal of Lipid Research, 2000 The objective of this study was to compare the long-term effects of oleic (cis 18:1), elaidic (trans 18:1), and palmitic (16:0) acids on hepatic lipoprotein production, using HepG2 cells as an experimental model.
Nassrin Dashti +2 more
doaj
Oil Content and Fatty Acid Composition of Safflower (Carthamus tinctorius L.) Germplasm
FoodsSafflower (Carthamus tinctorius L.) is a promising oilseed crop with potential applications in the food, pharmaceutical, and industrial sectors. Understanding the oil content and fatty acid composition of safflower germplasm is crucial for breeding ...
Cemal Kurt +5 more
doaj +1 more source