Results 41 to 50 of about 110,039 (337)

Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress. [PDF]

open access: yesPLoS ONE, 2015
Lipotoxicity plays an important role in pancreatic β-cell failure during the development of type 2 diabetes. Prolonged exposure of β-cells to elevated free fatty acids level could cause deterioration of β-cell function and induce cell apoptosis ...
Yuren Zhou   +5 more
doaj   +1 more source

Nutrients retention in functional beef burgers with especial emphasis on lipid profile [PDF]

open access: yes, 2014
The true retention values of nutrients, with particular reference to fatty acids of dietary importance, were investigated in burgers with none or half of the pork backfat replaced with soybean oil ?healthier burgers (HB)- added with 0g/kg, 5g/kg, 10g/kg
Doval, Mirtha Marina   +3 more
core   +1 more source

Risk of diabetes associated with fatty acids in the de novo lipogenesis pathway is independent of insulin sensitivity and response: the Insulin Resistance Atherosclerosis Study (IRAS)

open access: yesBMJ Open Diabetes Research & Care, 2019
Objective To examine the associations of fatty acids in the de novo lipogenesis (DNL) pathway, specifically myristic acid (14:0), palmitic acid (16:0), cis-palmitoleic acid (c16:1 n-7), cis-myristoleic acid (c14:1n5), stearic acid (18:0) and cis-oleic ...
Anthony J Hanley   +5 more
doaj   +1 more source

Enzymatic Formation of Hexadecenoic Acid from Palmitic Acid

open access: yesAgricultural and Biological Chemistry, 1975
Desaturation of palmitic acid was investigated in an enzyme system prepared from rat liver. 2-trans-Hexadecenoic acid as well as 9-cis-hexadecenoic acid (palmitoleic acid) were found to be formed as monoenoic acid in this system.
Masuo NAKANO, Yasuhiko FUJINO
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair [PDF]

open access: yes, 2017
High-fat diet-induced obesity is a major risk factor for osteoarthritis (OA) and diminished wound healing. The objective of this study was to determine the associations among serum and synovial fluid lipid levels with OA, synovitis, adipokine levels, and
Guilak, Farshid   +3 more
core   +2 more sources

Exogenous Oleic Acid and Palmitic Acid Improve Boar Sperm Motility via Enhancing Mitochondrial Β-Oxidation for ATP Generation

open access: yesAnimals, 2020
It takes several hours for mammalian sperm to migrate from the ejaculation or insemination site to the fertilization site in the female reproductive tract in which glucose, amino acids, and fatty acids are regarded as the primary substrates for ATP ...
Zhendong Zhu   +9 more
doaj   +1 more source

Bioactive Compounds in Sarcocornia and Arthrocnemum, Two Wild Halophilic Genera from the Iberian Peninsula

open access: yesPlants, 2021
(1) Background: this study describes bioactive compounds in the following halophytes: Sarcocornia (S. alpini, S. pruinosa, and S. perennis) and Arthrocnemum (A. macrostachyum).
Irene Sánchez-Gavilán   +2 more
doaj   +1 more source

Relative utilization of free palmitic acid, glyceryl palmitate and ethyl palmitate by dogs [PDF]

open access: yesExperimental Biology and Medicine, 1917
Digestibility of fats depends on several factors which may be grouped as: (1) mechanical, e. g., melting point which determines the rate of gastric discharge1 and, to a considerable extent, the degree of emulsification; and (2) chemical which determines the character of the products of digestion and the rate of hydrolysis, certain esters of fatty acids,
openaire   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

open access: yesAdvanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu   +14 more
wiley   +1 more source

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