Results 41 to 50 of about 106,933 (288)

Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E2 [PDF]

, 2019
Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens. Here, we discovered that MDV activates the fatty acid synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEFs).
Behboudi, Shahriar, Boodhoo, Nitish, Kamble, Nitin, Kaufer, Benedikt B.   +3 more
core   +1 more source

Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress. [PDF]

PLoS ONE, 2015
Lipotoxicity plays an important role in pancreatic β-cell failure during the development of type 2 diabetes. Prolonged exposure of β-cells to elevated free fatty acids level could cause deterioration of β-cell function and induce cell apoptosis ...
Yuren Zhou, Peng Sun, Ting Wang, Kaixian Chen, Weiliang Zhu, Heyao Wang   +5 more
doaj   +1 more source

Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair [PDF]

, 2017
High-fat diet-induced obesity is a major risk factor for osteoarthritis (OA) and diminished wound healing. The objective of this study was to determine the associations among serum and synovial fluid lipid levels with OA, synovitis, adipokine levels, and
Guilak, Farshid, Kimmerling, Kelly A, Little, Dianne, Wu, Chia-Lung   +3 more
core   +2 more sources

Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis. [PDF]

, 2015
Palmitic acid (PA) induces hepatocyte apoptosis and fuels de novo ceramide synthesis in the endoplasmic reticulum (ER). Myristic acid (MA), a free fatty acid highly abundant in copra/palmist oils, is a predictor of nonalcoholic steatohepatitis (NASH) and
Alarcón-Vila, C, Baulies, A, Caballeria, J, Casas, J, Elena, M, Fabriàs, G, Fernandez-Checa, JC, García-Ruiz, C, Martinez Gili, L, Torres, S   +9 more
core   +2 more sources

Exogenous Oleic Acid and Palmitic Acid Improve Boar Sperm Motility via Enhancing Mitochondrial Β-Oxidation for ATP Generation

Animals, 2020
It takes several hours for mammalian sperm to migrate from the ejaculation or insemination site to the fertilization site in the female reproductive tract in which glucose, amino acids, and fatty acids are regarded as the primary substrates for ATP ...
Zhendong Zhu, Rongnan Li, Chengwen Feng, Ruifang Liu, Yi Zheng, S. A. Masudul Hoque, De Wu, Hongzhao Lu, Tao Zhang, Wenxian Zeng   +9 more
doaj   +1 more source

Bioactive Compounds in Sarcocornia and Arthrocnemum, Two Wild Halophilic Genera from the Iberian Peninsula

Plants, 2021
(1) Background: this study describes bioactive compounds in the following halophytes: Sarcocornia (S. alpini, S. pruinosa, and S. perennis) and Arthrocnemum (A. macrostachyum).
Irene Sánchez-Gavilán, Esteban Ramírez Chueca, Vicenta de la Fuente García   +2 more
doaj   +1 more source

Enzymatic Formation of Hexadecenoic Acid from Palmitic Acid

Agricultural and Biological Chemistry, 1975
Desaturation of palmitic acid was investigated in an enzyme system prepared from rat liver. 2-trans-Hexadecenoic acid as well as 9-cis-hexadecenoic acid (palmitoleic acid) were found to be formed as monoenoic acid in this system.
Masuo NAKANO, Yasuhiko FUJINO
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Relative utilization of free palmitic acid, glyceryl palmitate and ethyl palmitate by dogs [PDF]

Experimental Biology and Medicine, 1917
Digestibility of fats depends on several factors which may be grouped as: (1) mechanical, e. g., melting point which determines the rate of gastric discharge1 and, to a considerable extent, the degree of emulsification; and (2) chemical which determines the character of the products of digestion and the rate of hydrolysis, certain esters of fatty acids,
openaire   +1 more source