Results 121 to 130 of about 20,725 (233)

Protein Palmitoylation and Pathogenesis in Apicomplexan Parasites

open access: yes, 2020
Apicomplexan parasites comprise a broad variety of protozoan parasites, including Toxoplasma gondii, Plasmodium, Eimeria, and Cryptosporidium species.
Marina Cecilia Caballero   +2 more
core  

Advances in understanding palmitoylation in female reproductive disorders: mechanisms and future directions

open access: yesMedicine Plus
Protein palmitoylation modification is a key lipidated post-translational modification that dynamically regulates protein function, subcellular localization, and signaling pathways in eukaryotic cells, with important implications for the onset and ...
Zhenteng Liu   +5 more
doaj   +1 more source

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

open access: yesThe FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar   +3 more
wiley   +1 more source

The on-off story of protein palmitoylation

open access: yes, 2003
Palmitoylation is one of the most frequent post-translational modifications found on proteins. It contributes to membrane association, protein sorting and many other processes.
Marsh, M, Bijlmakers, M J
core   +1 more source

The emerging role of the Hippo signaling pathway in interorgan crosstalk

open access: yesThe FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song   +2 more
wiley   +1 more source

Characterizing Palmitoylation On The Sodium Hydrogen Exchanger Isoform 1 (NHE1)

open access: yes, 2020
This dissertation focuses on the role of palmitoylation in regulating the sodium hydrogen exchanger isoform 1 (NHE1) and associated cellular functions as well as how various phosphorylation pathways alter NHE1 palmitoylation.
Hovde, Moriah
core  

Timing of palmitoylation of influenza virus hemagglutinin

open access: yes, 1993
The timing of the attachment of fatty acids to the hemagglutinin (HA) of influenza A virus was studied. Treatment of virus infected cells with brefeldin A (BFA), a drug which blocks intracellular transport along the exocytic pathway at a pre-Golgi site ...
Veit, Michael   +3 more
core   +1 more source

Context-dependent roles of palmitoylation in acute respiratory distress syndrome: integrating inflammation, cell death and repair

open access: yesEuropean Respiratory Review
Acute respiratory distress syndrome (ARDS) is a life-threatening condition characterised by dysregulated inflammation, immune imbalance and impaired alveolar repair.
Qimin Ma, Yusong Wang, Feng Zhu
doaj   +1 more source

Bio‐active designed peptide for hair keratin strengthening

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Bioactive tripeptides through in silico screening revealed KCV (Tripeptide‐132) as the most promising keratin‐targeting candidate. Experimental studies confirmed its superior hair‐strengthening performance with 44% tensile strength enhancement, 50% breakage reduction, improved surface integrity and fibre penetration.
Chan‐Su Rha   +6 more
wiley   +1 more source

Enhancing Gpx1 palmitoylation to inhibit angiogenesis by targeting PPT1

open access: yesRedox Biology
The significance of protein S-palmitoylation in angiogenesis has been largely overlooked, leaving various aspects unexplored. Recent identification of Gpx1 as a palmitoylated protein has generated interest in exploring its potential involvement in novel ...
Yidan Ma   +9 more
doaj   +1 more source

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