Results 31 to 40 of about 5,013 (195)

Comparison of the antiemetic efficacy of a combination of midazolam with ramosetron and midazolam with palonosetron for postoperative nausea and vomiting prophylaxis in laparoscopic cholecystectomy

Medicine, 2023
Background: A multimodal therapeutic strategy for preventing postoperative nausea and vomiting (PONV) benefits moderate- and high-risk surgical patients. We compared the efficacy of a combination of midazolam and ramosetron and a combination of midazolam
Jung A Lim, Sungbin Jo, Eunkyung Choi
semanticscholar   +1 more source

Comparison of palonosetron with ondansetron in prevention of postoperative nausea and vomiting in patients receiving intravenous patient-controlled analgesia after gynecological laparoscopic surgery [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundPostoperative nausea and vomiting (PONV) are common complications after anesthesia and surgery. This study was designed to compare the effects of palonosetron and ondansetron in preventing PONV in high-risk patients receiving intravenous opioid-
Yu Yil Kim, Soo Yeong Moon, Dong Un Song, Ki Hyun Lee, Jae Wook Song, Young Eun Kwon   +5 more
doaj   +1 more source

Netupitant/palonosetron (NEPA; Akynzeo®) combination in prevention of the nausea and vomiting in patients with breast cancer receiving anthracyclinbased chemotherapy

Опухоли женской репродуктивной системы, 2023
Chemotherapy-induced nausea and vomiting is a common problem during cancer treatment, especially in breast cancer patients with anthracycline/cyclophosphamide (ас) chemotherapy.
A. G. Kedrova, A. I. Berishvili
doaj   +1 more source

Application of Box-Behnken design for optimization of A RP-HPLC method for determination of palonosetron and netupitant in their combined dosage form in presence of their impurities

Journal of Liquid Chromatography & Related Technologies, 2022
The use of (Netupitant and Palonosetron) combination to treat nausea and vomiting in cancer chemotherapy patients has been authorized by the Food and Drug Administration.
Mohamed A. ElHamid, Ehab F. Elkady, Eman A. Mostafa   +2 more
openalex   +3 more sources

Ocular Administration of Palonosetron in the Prevention of Cisplatin-Induced Nausea and Vomiting

Journal of Pharmacology and Experimental Therapeutics, 2023
Cancer treatments are frequently associated with nausea and vomiting despite greatly improved preventive medication. Administration of antinausea agents as eye drops might provide easy and rapid access to the systemic circulation for prevention of nausea
J. Levijoki, Lasse Saloranta, Johanna Tuunainen, Janne Kaskinoro, Sari Pappinen, S. Nourry, Anne-Marie Bétat, A. Maurin, Maarit Pakarinen, Sari Häkkinen, Johanna Tervapuro, Hertta Pihlasvaara, C. Drieu la Rochelle, H. Joensuu   +13 more
semanticscholar   +1 more source

Every‐other‐day palonosetron plus aprepitant for prevention of emesis following induction chemotherapy for acute myeloid leukemia: A randomized, controlled study from the “Rete Ematologica Pugliese”

Cancer Medicine, 2020
Background Compared with older 5‐HT3 receptor antagonists, palonosetron requires fewer drug administrations to prevent chemotherapy‐induced nausea and vomiting (CINV) following multiple‐day chemotherapy.
Nicola Di Renzo, Lorella Melillo, Fernando Porretto, Michela Dargenio, Vincenzo Pavone, Domenico Pastore, Patrizio Mazza, Donato Mannina, Anxur Merenda, Nicola Cascavilla, Giuseppina Greco, Rosella Matera, Erminio Bonizzoni, Luigi Celio, Maurizio Musso   +14 more
doaj   +1 more source

Efficacy of ondansetron and palonosetron in prevention of shivering under spinal anesthesia: A prospective randomized double-blind study in patients undergoing elective LSCS

Journal of Anaesthesiology Clinical Pharmacology, 2021
Background and Aims: Postanesthesia shivering (PAS) is a common, distressing experience. Ondansetron, the classical 5HT3 antagonist has been in use for its prevention since long.
Manoj K Sharma, Deepak Mishra, Nitin Goel   +2 more
doaj   +1 more source

Netupitant-palonosetron (NEPA) for Preventing Chemotherapy-induced Nausea and Vomiting: From Clinical Trials to Daily Practice

Current Cancer Drug Targets, 2022
Chemotherapy-induced nausea and vomiting (CINV) is a common adverse event associated with many anticancer therapies and can negatively impact patients' quality of life and potentially limit the effectiveness of chemotherapy.
M. Aapro, K. Jordan, F. Scotté, L. Celio, M. Karthaus, E. Roeland   +5 more
semanticscholar   +1 more source

Evaluating the impact of chemotherapy-induced nausea and vomiting on daily functioning in patients receiving dexamethasone-sparing antiemetic regimens with NEPA (netupitant/palonosetron) in the cisplatin setting: results from a randomized phase 3 study

BMC Cancer, 2022
The non-inferiority of dexamethasone (DEX) on day 1, with or without low-dose DEX on days 2 and 3, combined with oral NEPA (netupitant/palonosetron), compared with the guideline-consistent use of DEX was demonstrated in cisplatin.
L. Celio, D. Cortinovis, A. Cogoni, L. Cavanna, O. Martelli, S. Carnio, E. Collovà, F. Bertolini, F. Petrelli, A. Cassano, R. Chiari, F. Zanelli, S. Pisconti, I. Vittimberga, A. Letizia, A. Misino, A. Gernone, E. Bonizzoni, S. Pilotto, S. De Placido, E. Bria   +20 more
semanticscholar   +1 more source

Comparison of the Performance of Different Bile Salts in Enantioselective Separation of Palonosetron Stereoisomers by Micellar Electrokinetic Chromatography

Molecules, 2022
Bile salts are a category of natural chiral surfactants which have ever been used as the surfactant and chiral selector for the separation of many chiral compounds by micellar electrokinetic chromatography (MEKC).
Shaoqiang Hu, T. Sun, Rui Li, Dongdong Zhang, Yonghua Zhang, Zhuo Yang, Ge Feng, Xuming Guo   +7 more
semanticscholar   +1 more source