Consensus recommendations for the prevention of vomiting and nausea following high-emetic-risk chemotherapy [PDF]
, 2010 In this update of our 2005 document, we used an evidence-based approach whenever possible to formulate recommendations, emphasizing the results of controlled trials concerning the best use of antiemetic agents for the prevention of emesis and nausea ...
Ballatori, Enzo +11 more
core +1 more source
Phase II study of fosaprepitant + 5HT3 receptor antagonist + dexamethasone in patients with germ cell tumors undergoing 5-day cisplatin-based chemotherapy: A Hoosier Cancer Research Network Study [PDF]
, 2016 Purpose A phase III study adding aprepitant to a 5HT3 receptor antagonist (5HT3-RA) plus dexamethasone in germ cell tumor (GCT) patients treated with 5-day cisplatin combination chemotherapy demonstrated a significant improvement in complete response (
Adra, Nabil +11 more
core +2 more sources
Reasons for delayed patient discharge following day surgery: a literature review [PDF]
, 2016 NHS Trusts face considerable financial challenges. There is a drive to reduce costs by increasing day surgery rates, thereby reducing the length of post-operative stay.
Alison Rae, Rae, Alison
core +1 more source
BMC Anesthesiology, 2019 Background Hysterectomy is a widely performed surgery and neuraxial anesthesia with intrathecal morphine provides superior quality of recovery. Postoperative nausea and vomiting (PONV) is a frequent problem with intrathecal morphine use.
Guilherme Oliveira Campos +8 more
doaj +1 more source
PLoS ONE, 2016 Previous randomized controlled trials have reported conflicting findings on the superiority of palonosetron over ramosetron for preventing postoperative nausea and vomiting (PONV).
EunJin Ahn +7 more
doaj +1 more source
Journal of Anaesthesiology Clinical Pharmacology, 2019 Background and Aims: Postoperative nausea and vomiting (PONV) has multifactorial etiology. It is a commonly encountered morbidity after anesthesia specially following middle ear surgery. Various antiemetic medications have been tried with mixed responses.
Shubhangi Sharma +4 more
doaj +1 more source
A randomized, double-blind study to evaluate the efficacy of ramosetron and palonosetron for prevention of postoperative nausea and vomiting after gynecological laparoscopic surgery [PDF]
Korean Journal of Anesthesiology, 2013 BackgroundPostoperative nausea and vomiting (PONV) is a common complication after anesthesia and surgery; 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists have been considered as a first-line therapy.
Soo Kyoung Park +4 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Objective: To test the hypothesis that the single use of fosaprepitant is not inferior to the use of palonosetron as antiemetic prophylaxis in the first 48 h after surgery in women undergoing laparoscopic cholecystectomy.Method: Eighty-eight nonsmoking ...
Estêvão Luiz Carvalho Braga +2 more
doaj +1 more source
Effects of palonosetron and ondansetron on preventing nausea and vomiting after laparoscopic surgery
Journal of International Medical Research, 2018 Background This meta-analysis was performed to evaluate the efficacy and safety of palonosetron and ondansetron in preventing postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic surgery with general anesthesia.
Qili Liu +3 more
doaj +1 more source
A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research. [PDF]
, 2018 The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti-emetic properties and repurposing from one indication to another is a continuing trend.
Aapro +349 more
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