Results 141 to 150 of about 7,907 (187)

Enhanced transfection of primary cortical cultures using arginine-grafted PAMAM dendrimer, PAMAM-Arg

Journal of Controlled Release, 2006
PAMAM-Arg is a cationic arginine-grafted polyamidoamine (PAMAM) dendrimer. In the previous study, we reported that PAMAM-Arg facilitates transfection in a range of mammalian cell types. In the present study, we investigated the transfection efficiency of PAMAM-Arg in primary cortical cultures, which are known to be extremely vulnerable to exogenous ...
Jung-Bin Kim   +2 more
exaly   +3 more sources

The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers

Biomaterials, 2014
Poly(amidoamine) (PAMAM) dendrimers, are among the most common classes of dendrimers that are intended for a wide range of biomedical applications and extensively investigated for brain-specific drug delivery, imaging and diagnosis. Unfortunately, neurotoxicity of PAMAM dendrimers, the underlying mechanism of which is poorly-elucidated, poses a far ...
Shaofei Wang, Yubin Li, Jiajun Fan
exaly   +3 more sources

Conjugation of steroids with PAMAM nanoparticles

Colloids and Surfaces B: Biointerfaces, 2015
We studied the binding process between polyamidoamine PAMAN-G4 dendrimer and testosterone and its aliphatic (alip) and aromatic (arom) dimers in aqueous solution at pH 7.4. Multiple spectroscopic methods, transmission electron microscopy (TEM) and molecular modeling were used to characterize the steroid binding process to PAMAM-G4 nanoparticles ...
P, Chanphai   +2 more
openaire   +2 more sources

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