Results 161 to 170 of about 19,804 (212)
PAMAM dendrimer - cell membrane interactions
Advances in Colloid and Interface Science, 2018 PAMAM dendrimers have been conjectured for a wide range of biomedical applications due to their tuneable physicochemical properties. However, their application has been hindered by uncertainties in their cytotoxicity, which is influenced by dendrimer generation (i.e.
Wuge Briscoe
exaly +5 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Hierarchical polyion complex vesicles from PAMAM dendrimers
Journal of Colloid and Interface Science, 2022Hierarchical dendrimer-based polyion complex (PIC) vesicles with multiple compartments have attracted considerable attention as functional delivery vehicles and nano-carriers. Formation of these vesicles relies on the electrostatic assembly of asymmetric polyelectrolytes, namely branched dendrimers with linear polyion-neutral diblock copolymers ...
Chendan, Li +6 more
openaire +2 more sources
Design considerations for PAMAM dendrimer therapeutics
Bioorganic & Medicinal Chemistry Letters, 2013We have previously shown that methotrexate (MTX) conjugated to a cancer-specific poly amido amine (PAMAM) dendrimer has a higher therapeutic index than MTX alone. Unfortunately, these therapeutics have been difficult to advance because of the complicated syntheses and an incomplete understanding of the dendrimer properties.
Sascha N, Goonewardena +7 more
openaire +2 more sources
Conjugation of steroids with PAMAM nanoparticles
Colloids and Surfaces B: Biointerfaces, 2015We studied the binding process between polyamidoamine PAMAN-G4 dendrimer and testosterone and its aliphatic (alip) and aromatic (arom) dimers in aqueous solution at pH 7.4. Multiple spectroscopic methods, transmission electron microscopy (TEM) and molecular modeling were used to characterize the steroid binding process to PAMAM-G4 nanoparticles ...
P, Chanphai +2 more
openaire +2 more sources
PAMAM-PEG-PAMAM: Novel Triblock Copolymer as a Biocompatible and Efficient Gene Delivery Carrier
Biomacromolecules, 2004A novel triblock copolymer, PAMAM-block-PEG-block-PAMAM was synthesized and applied as a gene carrier. PAMAM dendrimer is proven to be an efficient gene carrier itself, but it is associated with certain problems such as low water solubility and considerable cytotoxicity.
Tae-Il, Kim +6 more
openaire +2 more sources
Journal of Biomaterials Science, Polymer Edition, 2015
Achieving biomimetic mineralization of collagen fibrils by mimicking the role of non-collagenous proteins (NCPs) with biomimetic analogs is of great interest in the fields of material science and stomatology. Amine-terminated PAMAM dendrimer (PAMAM-NH2), which possesses a highly ordered architecture and many calcium coordination sites, may be a ...
Kunneng, Liang +6 more
openaire +2 more sources
Achieving biomimetic mineralization of collagen fibrils by mimicking the role of non-collagenous proteins (NCPs) with biomimetic analogs is of great interest in the fields of material science and stomatology. Amine-terminated PAMAM dendrimer (PAMAM-NH2), which possesses a highly ordered architecture and many calcium coordination sites, may be a ...
Kunneng, Liang +6 more
openaire +2 more sources
Au(III)–PAMAM Interaction and Formation of Au–PAMAM Nanocomposites in Ethyl Acetate
Journal of Colloid and Interface Science, 2001Abstract The interaction of tetrachloroauric anion (AuCl4−) and hydrophobic poly(amidoamine) dendrimers (PAMAM) with terminal methyl ester groups was investigated in ethyl acetate by UV–vis and IR spectroscopies. Three possible types of interaction are suggested: (a) ion pair formation between AuCl4− and protonated tertiary amine of PAMAM, (b ...
Kanjiro Torigoe +2 more
openaire +1 more source
Tetrahedron, 2006
Azide-functionalized PAMAM dendrons containing an azidopropylamine focal point were synthesized by the divergent method and applied for the construction of symmetric PAMAM-like dendrimers containing 1,2,3-triazole rings as connectors via stitching with two different multi-terminal alkynes. The stitching method was based on the click chemistry protocol,
Jae Wook Lee +5 more
openaire +1 more source
Azide-functionalized PAMAM dendrons containing an azidopropylamine focal point were synthesized by the divergent method and applied for the construction of symmetric PAMAM-like dendrimers containing 1,2,3-triazole rings as connectors via stitching with two different multi-terminal alkynes. The stitching method was based on the click chemistry protocol,
Jae Wook Lee +5 more
openaire +1 more source
2005
(MW ) (high loading beads;1 single bead analysis;2, 3 water compatible, synthesis of peptides;1-3 dendrimer-chlorambucil conjugate;3 aryl ethers;4 amidines-based GP IIb-IIa antagonists;5 benzodiazepinone derivatives;6 diketopiperazine;7 secondary amide;6 biaryl;6 tetrazole;6 site-site interactions.7) Alternate Name: DendroGel.4
Siew-Eng How, Mark Bradley
openaire +1 more source
(MW ) (high loading beads;1 single bead analysis;2, 3 water compatible, synthesis of peptides;1-3 dendrimer-chlorambucil conjugate;3 aryl ethers;4 amidines-based GP IIb-IIa antagonists;5 benzodiazepinone derivatives;6 diketopiperazine;7 secondary amide;6 biaryl;6 tetrazole;6 site-site interactions.7) Alternate Name: DendroGel.4
Siew-Eng How, Mark Bradley
openaire +1 more source
Self‐assembled PAMAM dendrimer films
Advanced Materials, 1997Self‐assembly of starburst dendrimers into closely packed cells (see the optical micrograph in the Figure) is reported for generation 9.5 polyamidoamine (PAMAM) dendrimers solvent‐cast onto hydrophilic silicon substrates. It is shown that on the microscopic scale the cells are made up of a complex network of intertwined dendritic microfibrils ...
Simon A. Evenson, Jas Pal S. Badyal
openaire +1 more source