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Biomimetic mineralization of collagen fibrils induced by amine-terminated PAMAM dendrimers – PAMAM dendrimers for remineralization

Journal of Biomaterials Science, Polymer Edition, 2015
Achieving biomimetic mineralization of collagen fibrils by mimicking the role of non-collagenous proteins (NCPs) with biomimetic analogs is of great interest in the fields of material science and stomatology. Amine-terminated PAMAM dendrimer (PAMAM-NH2), which possesses a highly ordered architecture and many calcium coordination sites, may be a ...
Kunneng, Liang   +6 more
openaire   +2 more sources

Synthesis of Symmetrical and Unsymmetrical PAMAM Dendrimers by Fusion between Azide- and Alkyne-Functionalized PAMAM Dendrons

Bioconjugate Chemistry, 2007
A new convergent synthetic method for the synthesis of PAMAM dendrimers has been developed. The fusion between propargyl-functionalized PAMAM dendrons and azido-functionalized PAMAM dendrons via the Cu(I)-catalyzed Huisgen [2 + 3] dipolar cycloaddition reaction (click chemistry) of an alkyne and an azide leads to the formation of symmetric PAMAM ...
Jae Wook, Lee   +6 more
openaire   +2 more sources

Convergent synthesis of PAMAM dendrimers using click chemistry of azide-functionalized PAMAM dendrons

Tetrahedron, 2006
Azide-functionalized PAMAM dendrons containing an azidopropylamine focal point were synthesized by the divergent method and applied for the construction of symmetric PAMAM-like dendrimers containing 1,2,3-triazole rings as connectors via stitching with two different multi-terminal alkynes. The stitching method was based on the click chemistry protocol,
Jae Wook Lee   +5 more
openaire   +1 more source

CuO nanoparticles with PAMAM dendrimers

Journal of Coordination Chemistry, 2016
AbstractAn easy pathway to synthesize a variety of cupric oxide (CuO) nanoshapes by a one-step wet chemical method is reported. CuO nanoparticles and nanorods were obtained from CuCl2 in a mixture of water and DMSO in the absence of a base at room temperature.
A. R. Vázquez-Olmos   +4 more
openaire   +1 more source

PAMAM Dendrimers: Destined for Success or Doomed to Fail? Plain and Modified PAMAM Dendrimers in the Context of Biomedical Applications

Journal of Pharmaceutical Sciences, 2015
PAMAM (polyamidoamine) dendrimers are commonly considered promising polymers that can be successfully used in various biomedical applications. Nevertheless, direct clinical adaptations of plain unmodified PAMAM dendrimers may be limited at present, mainly because of their toxicity, unpredictable behavior in living organisms, unknown bioavailability ...
Magdalena, Labieniec-Watala   +1 more
openaire   +2 more sources

Synthesis of azide-functionalized PAMAM dendrons at the focal point and their application for synthesis of PAMAM-like dendrimers

Tetrahedron Letters, 2006
For the first time, the divergent synthesis of azide-functionalized PAMAM dendrons using azidopropyl amine as an azide focal point and convergent synthesis of symmetric PAMAM-like dendrimers containing 1,2,3-triazole rings as connectors via click chemistry with a dialkyne core is described.
Jae Wook Lee   +2 more
openaire   +1 more source

Nanoscale Protein Pores Modified with PAMAM Dendrimers

Journal of the American Chemical Society, 2007
We describe nanoscale protein pores modified with a single hyperbranched dendrimer molecule inside the channel lumen. Sulfhydryl-reactive polyamido amine (PAMAM) dendrimers of generations 2, 3 and 5 were synthesized, chemically characterized, and reacted with engineered cysteine residues in the transmembrane pore alpha-hemolysin.
Hugh, Martin   +5 more
openaire   +2 more sources

Fluorescence Analysis Of PAMAM Dendrimers

2023
Despite their lack of conjugation, polyamidoamine (PAMAM) dendrimers are intrinsically fluorescent, and this fluorescent is somewhat manipulable through altering the dendrimer's solvent. This level of fluorescence is dependent on a number of the dendrimer's qualities: the pH of the solvent, the mass percent concentration of the dendrimer in solvent ...
openaire   +1 more source

Association of small aromatic molecules with PAMAM dendrimers

Physical Chemistry Chemical Physics, 2015
Dendrimer pockets enable association by reducing naphthalene hydration even near the dendrimer periphery.
Ryan S, DeFever, Sapna, Sarupria
openaire   +2 more sources

PAMAM dendrimers: A multifunctional nanomaterial for ECL biosensors

Talanta, 2017
Polyamido amine (PAMAM) dendrimers have been shown to function as electrochemiluminescence (ECL) co-reactant and have the inherent capability of improving immobilization of molecules on surfaces due to their dendritic structure. Here, we investigated the combination of both of these properties as the basis for biosensor development.
Sudeshna, Chandra   +2 more
openaire   +2 more sources

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