Results 181 to 190 of about 13,057 (214)
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Toxicity of PAMAM dendrimers to Chlamydomonas reinhardtii
Aquatic Toxicology, 2010In recent decades, a new class of polymeric materials, PAMAM dendrimers, has attracted marked interest owing to their unique nanoscopic architecture and their hopeful perspectives in nanomedicine and therapeutics. However, the potential release of dendrimers into the aquatic environment raises the issue about their toxicity on aquatic organisms.
Anne-Noëlle, Petit +3 more
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Journal of Biomaterials Science, Polymer Edition, 2015
Achieving biomimetic mineralization of collagen fibrils by mimicking the role of non-collagenous proteins (NCPs) with biomimetic analogs is of great interest in the fields of material science and stomatology. Amine-terminated PAMAM dendrimer (PAMAM-NH2), which possesses a highly ordered architecture and many calcium coordination sites, may be a ...
Kunneng, Liang +6 more
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Achieving biomimetic mineralization of collagen fibrils by mimicking the role of non-collagenous proteins (NCPs) with biomimetic analogs is of great interest in the fields of material science and stomatology. Amine-terminated PAMAM dendrimer (PAMAM-NH2), which possesses a highly ordered architecture and many calcium coordination sites, may be a ...
Kunneng, Liang +6 more
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New Advances in General Biomedical Applications of PAMAM Dendrimers
Molecules, 2018 Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by Donald A. Tomalia, as a new class of polymers, named ‘starburst polymers’.
Jeanine Giarolla Vargas +2 more
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Functionalized PAMAM constructed nanosystems for biomacromolecule delivery
Biomaterials Science, 2023Strategies for functionalization of PAMAM-based biomacromolecule delivery systems.
Ka Hong Wong +3 more
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CuO nanoparticles with PAMAM dendrimers
Journal of Coordination Chemistry, 2016AbstractAn easy pathway to synthesize a variety of cupric oxide (CuO) nanoshapes by a one-step wet chemical method is reported. CuO nanoparticles and nanorods were obtained from CuCl2 in a mixture of water and DMSO in the absence of a base at room temperature.
A. R. Vázquez-Olmos +4 more
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Journal of Pharmaceutical Sciences, 2015
PAMAM (polyamidoamine) dendrimers are commonly considered promising polymers that can be successfully used in various biomedical applications. Nevertheless, direct clinical adaptations of plain unmodified PAMAM dendrimers may be limited at present, mainly because of their toxicity, unpredictable behavior in living organisms, unknown bioavailability ...
Magdalena, Labieniec-Watala +1 more
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PAMAM (polyamidoamine) dendrimers are commonly considered promising polymers that can be successfully used in various biomedical applications. Nevertheless, direct clinical adaptations of plain unmodified PAMAM dendrimers may be limited at present, mainly because of their toxicity, unpredictable behavior in living organisms, unknown bioavailability ...
Magdalena, Labieniec-Watala +1 more
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Binding analysis of antioxidant polyphenols with PAMAM nanoparticles
Journal of Biomolecular Structure and Dynamics, 2017Dietary polyphenols are abundant micronutrients in our diet and paly major role in prevention of degenerative diseases. The binding efficacy of antioxidant polyphenols resveratrol, genistein, and curcumin with PAMAM-G3 and PAMAM-G4 nanoparticles was investigated in aqueous solution at physiological conditions, using multiple spectroscopic methods, TEM ...
P, Chanphai, H A, Tajmir-Riahi
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Tetrahedron Letters, 2006
For the first time, the divergent synthesis of azide-functionalized PAMAM dendrons using azidopropyl amine as an azide focal point and convergent synthesis of symmetric PAMAM-like dendrimers containing 1,2,3-triazole rings as connectors via click chemistry with a dialkyne core is described.
Jae Wook Lee +2 more
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For the first time, the divergent synthesis of azide-functionalized PAMAM dendrons using azidopropyl amine as an azide focal point and convergent synthesis of symmetric PAMAM-like dendrimers containing 1,2,3-triazole rings as connectors via click chemistry with a dialkyne core is described.
Jae Wook Lee +2 more
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Nanoscale Protein Pores Modified with PAMAM Dendrimers
Journal of the American Chemical Society, 2007We describe nanoscale protein pores modified with a single hyperbranched dendrimer molecule inside the channel lumen. Sulfhydryl-reactive polyamido amine (PAMAM) dendrimers of generations 2, 3 and 5 were synthesized, chemically characterized, and reacted with engineered cysteine residues in the transmembrane pore alpha-hemolysin.
Hugh, Martin +5 more
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PAMAM Dendrimers as Delivery Agents for Antisense Oligonucleotides
Pharmaceutical Research, 1999To investigate the potential use of PAMAM dendrimers for the delivery of antisense oligonucleotides into cells under conditions that mimic the in vivo environment.We used HeLa cells stably transfected with plasmid pLuc/705 which has a luciferase gene interrupted by a human beta-globin intron mutated at nucleotide 705, thus causing incorrect splicing ...
H, Yoo, P, Sazani, R L, Juliano
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