Results 151 to 160 of about 9,478 (168)

Functional hydrophilic highly biodegradable PCL nanofibers through direct aminolysis of PAMAM dendrimer

International Journal of Polymeric Materials and Polymeric Biomaterials, 2020
Polycaprolactone (PCL) was modified with second-generation poly(amidoamine) dendrimer (PAMAM-G2) in electrospinning solution through aminolysis of PCL ester bonds. Two factors affected the modification of PCL in the presence of PAMAM dendrimer.
Pouyan Razmshoar, S. Bahrami, S. Akbari
semanticscholar   +1 more source

Surface modified PAMAM dendrimers with gallic acid inhibit, cell proliferation, cell migration and inflammatory response to augment apoptotic cell death in human colon carcinoma cells

Journal of Biomolecular Structure and Dynamics, 2020
To overcome the obstacle of anti-cancer therapy significant attention has been drawn for improving drug delivery system. Since recent past, different approaches were applied using synthetic or natural derivatives for improving efficacy of anti-cancer ...
Khushbu Priyadarshi, K. Shirsath, N. B. Waghela, Anupama Sharma, Ajay Kumar, C. Pathak   +5 more
semanticscholar   +1 more source

PAMAM Dendrimer as a Talented Multifunctional Biomimetic Nanocarrier for Cancer Diagnosis and Therapy

, 2020
Poly(amidoamine) dendrimers (PAMAM) are novel polymeric highly branched architectures with well-defined nano-size, narrow polydispersity index and numerous active amine functional groups at the periphery.
B. Surekha, S. Dubey, N. Kommana, Prashant Kesharwani   +3 more
semanticscholar   +1 more source

PAMAM G4.5 dendrimers for targeted delivery of ferulic acid and paclitaxel to overcome P‐glycoprotein‐mediated multidrug resistance

Biotechnology and Bioengineering, 2020
In this study, we prepared ferulic acid (FA) and paclitaxel (PTX) co‐loaded polyamidoamine (PAMAM) dendrimers conjugated with arginyl–glycyl–aspartic acid (RGD) to overcome P‐glycoprotein (P‐gp)‐mediated multidrug resistance (MDR).
R. Anbazhagan, Ganesan Muthusamy, Rajakumari Krishnamoorthi, Swedha Kumaresan, R. Nagarajan, J. Lai, Jen-Ming Yang, Hsieh‐Chih Tsai   +7 more
semanticscholar   +1 more source

Lactoferrin Coupled Lower Generation PAMAM Dendrimers for Brain Targeted Delivery of Memantine in Aluminum-Chloride-Induced Alzheimer's Disease in Mice.

Bioconjugate chemistry, 2019
Lower generation PAMAM dendrimers have an immense potential for drug delivery with lower toxicity, but these dendrimers yet need certain basic ameliorations.
Avinash Gothwal, H. Kumar, K. T. Nakhate, Ajazuddin, Ankumoni Dutta, Anupom Borah, U. Gupta   +6 more
semanticscholar   +1 more source

Gold nanoparticles standing on PEG/PAMAM/thiol-functionalized nanographene oxide as aqueous catalysts

, 2020
Taking advantage of biocompatible poly(ethylene glycol) and hyperbranched polyamidamine (PAMAM) dendrimer, two polymer/thiol-functionalized nanographene oxide platforms (SH-NGO-PEG and SH-PAMAM-NGO-PEG) with well dispersity and adequate thiol active ...
Bingjie Hao, Guolin Lu, Sen Zhang, Yongjun Li, A. Ding, Xiaoyu Huang   +5 more
semanticscholar   +1 more source

Co-delivery of doxorubicin and TRAIL plasmid by modified PAMAM dendrimer in colon cancer cells, in vitro and in vivo evaluation

Drug Development and Industrial Pharmacy, 2019
One strategy for cancer treatment is combination therapy using nanoparticles (NPs), which has resulted in enhanced anti-cancer effects and reduced cytotoxicity of therapeutic agents.
Elham Pishavar, M. Ramezani, M. Hashemi
semanticscholar   +1 more source

PAMAM dendrimer as a talented multifunctional biomimetic nanocarrier for cancer diagnosis and therapy.

Colloids and Surfaces B: Biointerfaces, 2021
B. Surekha, N. Kommana, S. Dubey, A.V. Pavan Kumar, R. Shukla, Prashant Kesharwani   +5 more
semanticscholar   +1 more source

Intratumor Performance and Therapeutic Efficacy of PAMAM Dendrimers Carried by Clustered Nanoparticles.

Nano letters (Print), 2019
In recent years, small nanoparticles (NPs) with a diameter of less than 10 nm have aroused considerable interest in biomedical applications. However, their intratumor performance, as well as the antitumor efficacy, has not been well understood due to ...
Hong-Jun Li, Jing Liu, Yingli Luo, Senbiao Chen, Rong Liu, Jin-Zhi Du, Jun Wang   +6 more
semanticscholar   +1 more source

Cholesterol‐conjugated PEGylated PAMAM as an efficient nanocarrier for plasmid encoding interleukin‐12 immunogene delivery toward colon cancer cells

Biotechnology progress (Print), 2019
IL‐12 is a pleiotropic cytokine, which shows an ideal applicant for tumor immunotherapy, because of its features of creating an interconnection between innate (NK cells) and adaptive (cytotoxic T lymphocyte) immunity.
Elham Pishavar, Fatemeh Oroojalian, M. Ramezani, M. Hashemi   +3 more
semanticscholar   +1 more source