Results 31 to 40 of about 7,634 (170)
Nanomaterials, 2019 Polyamidoamine (PAMAM) dendrimers are efficient drug carriers. The presence of a physiological pathway for nasal brain transport provides a potential path for direct brain-targeted delivery of dendrimer nanocomposites. In this study, we synthesized PAMAM
Huichao Xie +9 more
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Nanomaterials, 2019 Dentin hypersensitivity (DH) is one of the most common clinical conditions usually associated with exposed dentinal surfaces. In this study, we identified the effectiveness of poly(amidoamine) (PAMAM) dendrimer-coated mesoporous bioactive glass ...
Jungin Bae +8 more
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Molecules, 2013 Erythromycin (EM) and tobramycin (TOB) are well-known and widely used antibiotics, belonging to different therapeutic groups: macrolide and aminoglycoside, respectively.
Elzbieta Anna Tryniszewska +4 more
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Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Intrinsic Fluorescence of PAMAM Dendrimers—Quenching Studies [PDF]
Polymers, 2018 Intrinsic, non-traditional fluorescence of polyamidoamine (PAMAM) dendrimers that do not possess classical fluorophores has been attracting considerable interest for the last decade. Many hypotheses regarding the source of the fluorescence have appeared, but some of them are still disputable.
Malgorzata Konopka +2 more
openaire +2 more sources
PAMAM dendrimers based co-delivery of methotrexate and berberine for targeting of Hela cancer cells
Toxicology ReportsPolyamidoamine dendrimer (PAMAM) is a class of synthetic macromolecular polymers for targeted drug delivery. PAMAM dendrimers are characterized by a pure defined structure, adjustable nanoscale dimensions, mono-dispersity, and versatile surface ...
Hossein Majidzadeh +8 more
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Nano Biomedicine and Engineering, 2010 With the aim of observing morphological changes of pancreatic cancer cells transfected by PAMAM dendrimer modified single walled carbon nanotubes(SWCNT-PAMAM complexes), the SWCNT-PAMAM complexes were prepared and characterized by atom force microscopy ...
Dongfeng Chen +5 more
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Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease
Advanced Materials, EarlyView.RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley +1 more source
Advanced Materials Technologies, EarlyView.ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali +4 more
wiley +1 more source
Advanced Science, EarlyView.Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang +9 more
wiley +1 more source