Results 71 to 80 of about 26,467 (310)

Dendritic glycopolymers based on dendritic polyamine scaffolds: view on their synthetic approaches, characteristics and potential for biomedical applications [PDF]

open access: yes, 2014
In this review we highlight the potential for biomedical applications of dendritic glycopolymers based on polyamine scaffolds. The complex interplay of the molecular characteristics of the dendritic architectures and their specific interactions with ...
Abbott   +278 more
core   +2 more sources

Dendrimer Assisted Dispersion of Carbon Nanotubes: A Molecular Dynamics Study [PDF]

open access: yesSoft Matter, 2016,12, 8512-8520, 2016
Various unique physical, chemical, mechanical and electronic properties of carbon nanotube (CNT) make it very useful materials for diverse potential application in many fields. Experimentally synthesized CNTs are generally found in bundle geometry with a mixture of different chirality and present a unique challenge to separate them.
arxiv   +1 more source

New Advances in General Biomedical Applications of PAMAM Dendrimers

open access: yesMolecules, 2018
Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by Donald A. Tomalia, as a new class of polymers, named ‘starburst polymers’.
Renan Vinícius de Araújo   +3 more
semanticscholar   +1 more source

Nucleic Acid Carriers Based on Precise Polymer Conjugates [PDF]

open access: yes, 2011
Polymer polydispersity, random conjugation of functional groups, and poorly understood structure–activity relationships have constantly hampered progress in the development of nucleic acid carriers.
Troiber, Christina, Wagner, Ernst
core   +1 more source

Bioconjugation of biotinylated PAMAM dendrons to avidin

open access: yesChemical Communications, 2007
The biotin-terminated PAMAM dendron has been synthesized and the asymmetric dendron used to modify the protein avidin via non-covalent bioconjugation.
Tao, L.   +6 more
openaire   +4 more sources

Nanotoxicology of Dendrimers in the Mammalian Heart: ex vivo and in vivo Administration of G6 PAMAM Nanoparticles Impairs Recovery of Cardiac Function Following Ischemia-Reperfusion Injury

open access: yesInternational Journal of Nanomedicine, 2020
Fawzi Babiker,1 Ibrahim F Benter,2 Saghir Akhtar3 1Department of Physiology, Faculty of Medicine, Health Science Center, Kuwait University, Kuwait City, Kuwait; 2Faculty of Medicine, Eastern Mediterranean University, Famagusta, North Cyprus, Republic of ...
Babiker F, Benter IF, Akhtar S
doaj  

PAMAM Dendrimers Undergo pH Responsive Conformational Changes without Swelling [PDF]

open access: yes, 2009
Atomistic molecular dynamics (MD) simulations of a G4-NH2 PAMAM dendrimer were carried out in aqueous solution using explicit water molecules and counterions (with the Dreiding III force field optimized using quantum mechanics).
Bryantsev, Vyacheslav S.   +3 more
core   +2 more sources

PAMAM-G4 protect the N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) and maintain its antiproliferative effects on MCF-7

open access: yesScientific Reports, 2023
Our work group designed and synthesized a promissory compound N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA). The HO-AAVPA is a HDAC1 inhibitor and antiproliferative in cancer cell lines.
Alma Alicia Ortiz-Morales   +6 more
doaj   +1 more source

Polyamidoamine dendrimer impairs mitochondrial oxidation in brain tissue [PDF]

open access: yes, 2013
Background: The potential nanocarrier polyamidoamine (PAMAM) generation 5 (G5-NH2) dendrimer has been shown to evoke lasting neuronal depolarization and cell death in a concentration-dependent manner. In this study we explored the early progression of G5-
Benéné Visy, Júlia   +5 more
core   +1 more source

Slow-Release Formulation of Cowpea Mosaic Virus for In Situ Vaccine Delivery to Treat Ovarian Cancer. [PDF]

open access: yes, 2018
The plant viral nanoparticle cowpea mosaic virus (CPMV) is shown to be an effective immunotherapy for ovarian cancer when administered as in situ vaccine weekly, directly into the intraperitoneal (IP) space in mice with disseminated tumors.
Aguirre   +41 more
core   +2 more sources

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