Results 71 to 80 of about 9,478 (168)
Pharmaceutical Research, 2019 In order to overcome the obstacles and side effects of classical chemotherapy, numerous studies have been performed to develop the treatment based on targeted transport of active compounds directly to the site of action.
K. Sztandera +6 more
semanticscholar +1 more source
Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda +1 more
wiley +1 more source
Dendrimers bind antioxidant polyphenols and cisplatin drug.
PLoS ONE, 2012 Synthetic polymers of a specific shape and size play major role in drug delivery systems. Dendrimers are unique synthetic macromolecules of nanometer dimensions with a highly branched structure and globular shape with potential applications in gene and ...
Amine Abderrezak +4 more
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao +4 more
wiley +1 more source
Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells
Advanced Materials, Volume 38, Issue 3, 13 January 2026.Apolipoprotein nanoparticle (aNP) platform technology efficiently delivers RNA to immune cells following systemic administration. Here, it is demonstrated that incorporating polyvalent ionizable cationic dendrimers in aNPs enables robust mRNA complexation and functional delivery.
Mirre M. Trines +24 more
wiley +1 more source
Advanced Science, Volume 13, Issue 4, 19 January 2026.Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian +3 more
wiley +1 more source
On-Demand Bioadhesive Dendrimers with Reduced Cytotoxicity
Molecules, 2018 Tissue adhesives based on polyamidoamine (PAMAM) dendrimer, grafted with UV-sensitive aryldiazirine (PAMAM-g-diazirine) are promising new candidates for light active adhesion on soft tissues.
Feng Gao +5 more
doaj +1 more source
Pharmaceutics, 2018 We present here the development of multifunctional doxorubicin (DOX)-conjugated poly(amidoamine) (PAMAM) dendrimers as a unique platform for pH-responsive drug release and targeted chemotherapy of cancer cells.
Mengen Zhang +8 more
semanticscholar +1 more source
Supplementary Methods, Figure Legends 1-5 from Peptide-Conjugated PAMAM Dendrimer as a Universal DNA Vaccine Platform to Target Antigen-Presenting Cells [PDF]
, 2023 Pirouz Daftarian +14 more
openalex +1 more source