Results 81 to 90 of about 9,478 (168)
Metabolism‐Regulating Nanomedicines for Cancer Therapy
Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
Investigation of Dendriplexes by Ion Mobility-Mass Spectrometry
Molecules, 2014 Highly branched polyamidoamine (PAMAM) dendrimers presenting biological activities have been envisaged as non-viral gene delivery vectors. They are known to associate with nucleic acid (DNA) in non-covalent complexes via electrostatic interactions ...
Emma-Dune Leriche +6 more
doaj +1 more source
Combined Therapy for Alzheimer’s Disease: Tacrine and PAMAM Dendrimers Co-Administration Reduces the Side Effects of the Drug without Modifying its Activity [PDF]
, 2020 Daniela E. Igartúa +3 more
openalex +1 more source
Glucose‐Responsive Modified Poly(Propylene Imine) Dendrimer for Self‐Regulated Insulin Delivery
Macromolecular Materials and Engineering, Volume 311, Issue 1, January 2026.Poly(propylene imine) dendrimers functionalized with phenolboronic acid (PBA) are synthesized and modified to develop a glucose‐sensitive system with a pKa of ∼7.4. Also, the equilibrium binding constant (Keq‐tet) for PBA‐attached G4 dendrimer (HB‐CBA) was determined to be 79 m−1.
Amin Hosseini Sharifabad +2 more
wiley +1 more source
Molecules, 2018 The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the mechanism of PAMAM dendrimers with generation 0 to generation 3 (G0–G3) and concentrations (0 ...
Juan Lu +9 more
doaj +1 more source
International Journal of Molecular Sciences, 2019 Polyamidoamine (PAMAM) dendrimers are extensively researched as potential drug delivery system thanks to their desirable features such as controlled and stable structures, and ease of functionalization onto their surface active groups.
M. -. Vu +8 more
semanticscholar +1 more source
Advanced Macromolecular Architectures via Inorganic Polymers
Macromolecular Rapid Communications, Volume 47, Issue 2, 23 January 2026.From linear chains to advanced macromolecular architectures, this review explores how innovations in inorganic polymers unlock new structural and functional capabilities. Emphasizing modern synthetic strategies and unique architectural designs, it highlights the emerging potential of main‐group element systems as next‐generation alternatives to ...
Edip Ajvazi +3 more
wiley +1 more source
Pharmaceutics, 2018 l-cysteine (Cys)- and l-serine (Ser)-modified, third-generation polyamidoamine (PAMAM) dendrimer with multiple reduced thiols (Ser-PAMAM-Cys) was synthesized as a kidney-targeting reactive oxygen species (ROS) scavenger to help prevent renal ischemia ...
Satoru Matsuura +7 more
doaj +1 more source
Detection of dengue using PAMAM dendrimer integrated tapered optical fiber sensor
Scientific Reports, 2019 The exponential escalation of dengue cases has indeed become a global health crisis. This work elaborates on the development of a biofunctionalized tapered optical fiber (TOF) based sensor with the integration of polyamidoamine (PAMAM) dendrimer for the ...
Y. Mustapha Kamil +6 more
semanticscholar +1 more source
Nanotechnology‐Enhanced Approaches for Early Cancer Diagnosis
Nano Select, Volume 7, Issue 1, January 2026.Conventional MRI and PET provide limited sensitivity and contrast for precise brain lesion detection. In contrast, radiolabeled nanoparticlebased PET imaging enables enhanced signal specificity and sensitivity. By integrating multifunctional nanoprobes, this platform improves multimodal imaging performance, allowing more accurate visualization of ...
Jongmoo Lee +5 more
wiley +1 more source