Results 221 to 230 of about 27,901 (286)

Phenotypic Clustering of Idiopathic Pulmonary Arterial Hypertension: Insights Into Pulmonary Vascular and Cardiometabolic Co-Morbidity Trajectories. [PDF]

Pulm Circ
Kaymaz C, Kultursay B, Tokgoz HC, Tanyeri S, Bulus C, Keskin B, Cagliyan CE, Kibar M, Erdem C, Vezir A, Akkus I, Bulut M, Hakgor A, Tanboga IH, Ozdemir N.   +14 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, Volume 20, Issue 9, Page 2163-2174, September 2026.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

H3K27me3-Mediated Epigenetic Silencing of FgHMG1 Enables Fungal Host Immune Evasion. [PDF]

Plant Biotechnol J
Zhao X, Yuan B, Ma P, Cai Y, Huang Y, Wang Y, Cheng Z, Chen Y, Zheng M, Zhang R, Wu J, Li X, Wang M, Wu H, Zhang C, Gao X, Chen L, Gu Q.   +17 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, Volume 20, Issue 9, Page 2135-2162, September 2026.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Dynamic regulation of the BIK1-RIN4 complex determines plant immunity and effector-mediated virulence. [PDF]

New Phytol
Lee H, Ko D, Kang H, Jang E, Park OK, Kim SH, El-Kasmi F, Chung EH.   +7 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, Volume 16, Issue 9, Page 1657-1668, September 2026.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Refractory Behavior in Plant Cells-Calcium Signaling Induced by Biotic Stress. [PDF]

Plants (Basel)
Keßler MK, Fulek V, Niehaus K, Lutter P.   +3 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, Volume 16, Issue 9, Page 1766-1785, September 2026.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Crosstalk and reciprocal regulation of phosphorylation and ubiquitination mediated by receptor-like kinases and U-box E3 ligases during plant growth and environmental stress responses. [PDF]

Plant Commun
Li G, Peng Y, Sun M, Qin Z, Dai S.
europepmc   +1 more source

Challenges and Future Perspectives for Vaccines Targeting the Tumor Microenvironment. [PDF]

Vaccines (Basel)
Lowe DB, Feizi N, Storkus WJ.
europepmc   +1 more source