The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley +1 more source
The F-box Containing Bacterial Effector RipG6 Destabilizes a Receptor-Like Cytoplasmic Kinase Involved in Plant Immune Signaling. [PDF]
Jeon H +4 more
europepmc +1 more source
ABSTRACT Background Inflammatory pain is a widespread global health concern arising from complex molecular pathways triggered by a consequence of tissue damage and immune activation. It significantly impacts quality of life and functional outcomes, necessitating a comprehensive understanding of underlying mechanisms and multidisciplinary approaches for
Fatma Mohamed Elmansy +6 more
wiley +1 more source
DsRNA as pathogen-associated molecular pattern in innate immunity and multiple functions of the RNAi machinery complicate the use of RNAi in pest control. [PDF]
Feng M, Liu J, Wang L, Swevers L.
europepmc +1 more source
Vacuolization as a Novel Approach to Cancer Therapy
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak +9 more
wiley +1 more source
Innovative strategies for high-throughput discovery and engineering of plant immune receptors. [PDF]
Zhao W, Sun T, Zhang Y, Fu ZQ, Que Y.
europepmc +1 more source
RNAs Associated With Bacterial Outer Membrane Vesicles: Structural Insights Into Surface Composition
This work uncovers a new layer of bacterial communication. We show that RNAs, aided by the Hfq RNA‐chaperone, are not only packed inside Gram negative Outer Membrane Vesicles (OMVs) but can also be embedded in their membranes. This suggests that bacteria may use surface‐exposed RNAs to directly interact with host cells. Overall, our results broaden the
Kevin Mosca +4 more
wiley +1 more source
Prognostic Value of Right Ventricular Global Wasted Work in Precapillary Pulmonary Hypertension: A 3D Echocardiographic Study. [PDF]
Venkateshvaran A +6 more
europepmc +1 more source
Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro
Integrated secretome and phosphoprotein profiling of human nucleus pulposus cells revealed that IL‐1β and TLR2/6 activation induce a shared degenerative program, defined by consistent upregulation of IL‐6, IL‐8, GRO‐α, ICAM‐1, and MMP‐7 and convergence on NF‐κB/AP‐1 signaling.
Exarchos Kanelis +4 more
wiley +1 more source
Bioinspired protocells exhibiting anti-phytopathogenic properties. [PDF]
Riofrío W.
europepmc +1 more source

