Results 11 to 20 of about 244,634 (196)

Overcoming the Challenges of Phytochemicals in Triple Negative Breast Cancer Therapy: The Path Forward

open access: yesPlants, 2023
Triple negative breast cancer (TNBC) is a very aggressive subtype of breast cancer that lacks estrogen, progesterone, and HER2 receptor expression. TNBC is thought to be produced by Wnt, Notch, TGF-beta, and VEGF pathway activation, which leads to cell ...
Mohammed Alaouna   +8 more
doaj   +1 more source

Microbiomics in Collusion with the Nervous System in Carcinogenesis: Diagnosis, Pathogenesis and Treatment

open access: yesMicroorganisms, 2021
The influence of the naturally occurring population of microbes on various human diseases has been a topic of much recent interest. Not surprisingly, continuously growing attention is devoted to the existence of a gut brain axis, where the microbiota ...
Rodney Hull   +11 more
doaj   +1 more source

Exploiting the Molecular Basis of Oesophageal Cancer for Targeted Therapies and Biomarkers for Drug Response: Guiding Clinical Decision-Making

open access: yesBiomedicines, 2022
Worldwide, oesophageal cancer is the sixth leading cause of deaths related to cancer and represents a major health concern. Sub-Saharan Africa is one of the regions of the world with the highest incidence and mortality rates for oesophageal cancer and ...
Sikhumbuzo Mbatha   +2 more
doaj   +1 more source

En bloc resection of the external iliac vein along with broad ligament leiomyosarcoma: A case report

open access: yesCase Reports in Women's Health, 2019
Outcomes following the excision of the external iliac vein during gynaecological oncology surgery are poorly documented. This is because most gynaecological oncologists consider tumours with vascular involvement inoperable.
Fatima Ahmed   +5 more
doaj   +1 more source

Metastasis to para-aortic lymph nodes cephalad to the renal veins in patients with ovarian cancer

open access: yesWorld Journal of Surgical Oncology, 2020
Background In patients with epithelial ovarian cancer, whether metastasis to para-aortic lymph nodes located cephalad to the renal veins (supra-renal PAN) should be classified as regional lymph node metastasis or distant metastasis remains controversial.
Shinichi Komiyama   +4 more
doaj   +1 more source

Advertising of tobacco products at point of sale: who are more exposed in Brazil?

open access: yesSalud Pública de México, 2017
Objective. To describe the adult population perception of cigarette advertising at point of sale, according their tobaccouse status and socio-demographic characteristics such as sex, age, race/color, region, household location and schooling.
Adriana Bacelar Ferreira-Gomes   +5 more
doaj   +1 more source

TCGAplot: an R package for integrative pan-cancer analysis and visualization of TCGA multi-omics data

open access: yesBMC Bioinformatics, 2023
Background Pan-cancer analysis examines both the commonalities and heterogeneity among genomic and cellular alterations across numerous types of tumors.
Chenqi Liao, Xiong Wang
doaj   +1 more source

Screening and bioinformatics analysis of a ceRNA network based on the circular RNAs, miRNAs, and mRNAs in pan‐cancer

open access: yesCancer Medicine, 2020
Background The pan‐cancer analysis has recently brought us into a novel level of cancer research. Nowadays, the Circular RNAs (circRNAs) is becoming increasingly important in the occurrence and progression of tumors. Nevertheless, the specific expression
Zhanghan Chen   +4 more
doaj   +1 more source

Integrative omics analysis reveals effective stratification and potential prognosis markers of pan-gastrointestinal cancers

open access: yesiScience, 2021
Summary: Gastrointestinal (GI) tract cancers are the most common malignant cancers with high mortality rate. Pan-cancer multi-omics data fusion provides a powerful strategy to examine commonalities and differences among various cancer types and benefits ...
Huiting Jiangzhou   +7 more
doaj   +1 more source

Impact of between-tissue differences on pan-cancer predictions of drug sensitivity.

open access: yesPLoS Computational Biology, 2021
Increased availability of drug response and genomics data for many tumor cell lines has accelerated the development of pan-cancer prediction models of drug response.
John P Lloyd   +3 more
doaj   +1 more source

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