Results 21 to 30 of about 3,942,953 (265)

Regional collaboration for the development of national childhood cancer plans in Latin America and the Caribbean

open access: yesRevista Panamericana de Salud Pública, 2023
This article aims to describe the activities conducted by the National Childhood Cancer Plan Working Group to support the development of national childhood cancer plans in Latin America and the Caribbean in the period 2019–2022, and to present the stage ...
Patrícia Loggetto   +10 more
doaj   +1 more source

Causal associations of sleep traits with cancer incidence and mortality

open access: yesFrontiers in Genetics, 2023
To explore the correlation and causality between multidimensional sleep traits and pan-cancer incidence and mortality among patients with cancer. The multivariable Cox regression, linear and nonlinear Mendelian randomization (MR), and survival curve ...
Shanshan Tian   +14 more
doaj   +1 more source

Author Correction: Pan-cancer analysis of whole genomes.

open access: yes, 2023
In the published version of this paper, the list of members of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium and their affiliations contained minor errors in the affiliations. The original Article has been corrected to include the corrected
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium   +1 more
core   +1 more source

Pan-cancer landscape of homologous recombination deficiency [PDF]

open access: yes, 2020
Homologous recombination deficiency (HRD) results in impaired double strand break repair and is a frequent driver of tumorigenesis. Here, we develop a genome-wide mutational scarbased pan-cancer Classifier of HOmologous Recombination Deficiency (CHORD ...
Martens, John   +11 more
core   +2 more sources

Childhood, adolescent and young adult cancer: cancer trends report

open access: yes, 2023
This is the third Cancer Trends Report the National Cancer Registry Ireland (NCRI) has published on childhood cancers and the first to include cancers in adolescents and young adults (AYA) (up to 24 years of age).
National Cancer Registry Ireland (NCRI)
core  

Elimination of cervical cancer in Latin America (Project ECHO-ELA): lessons from phase one of implementation

open access: yesRevista Panamericana de Salud Pública, 2023
We describe the outcomes of The Extension for Community Healthcare Outcomes-Elimination of Cervical Cancer in The Americas (ECHO-ELA) program, which was developed as a tri-lateral cooperation between Pan American Health Organization (PAHO), the U.S ...
Samantha Batman   +13 more
doaj   +1 more source

HER3 Is an Actionable Target in Advanced Prostate Cancer.

open access: yes, 2021
It has been recognized for decades that ERBB signaling is important in prostate cancer, but targeting ERBB receptors as a therapeutic strategy for prostate cancer has been ineffective clinically.
Bertan, C   +44 more
core   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari   +5 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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