Results 51 to 60 of about 3,191,959 (309)
, 2007 Association studies in large series of breast cancer patients can be used to identify single-nucleotide polymorphisms (SNP) contributing to breast cancer susceptibility.
Pharoah, Paul DP +22 more
core +1 more source
Tumor-macrophage fusion hybrids contribute to radiation-induced progression of pancreatic cancer
, 2021 [[abstract]]Introduction: Fusion between cancer and myeloid cells contributes to malignant progression of cancer. Radiation has been shown to increase fusion hybrids during tissue regeneration.
Rathinasamy, B;Wang, CJ;Wan, SP;Chang, HJ
core +1 more source
, 2015 RAF and MEK inhibitors are effective in BRAF-mutant melanoma but not in BRAF-mutant colorectal cancer. To gain additional insights into this difference, we performed a genome-scale pooled shRNA enhancer screen in a BRAF-mutant, RAF inhibitor-resistant ...
Root, DE +5 more
core +1 more source
Circulating microRNAs as potential new biomarkers for prostate cancer [PDF]
, 2013 Since they were first described in the 1990s, circulating microRNAs (miRNAs) have provided an active and rapidly evolving area of current research that has the potential to transform cancer diagnostics and therapeutics.
Bevan, C. L. +11 more
core +1 more source
Systematic characterization of pan‐cancer mutation clusters
Molecular Systems Biology, 2018 Molecular Systems Biology, 14 (3)
Marija Buljan +3 more
openaire +5 more sources
A pan-cancer analysis of the FAT1 in human tumors
Scientific Reports, 2022 AbstractFAT atypical cadherin 1 (FAT1) is one of the most mutagenic genes in tumors, and several critical studies have revealed its role in tumors, although no pan-cancer studies are currently available. Therefore, we explored the potential oncogenic role of FAT1 in 33 tumors based on The Cancer Genome Atlas and Gene Expression Omibus datasets.
Ziyao Wang, Kang Lin, Hai Xiao
openaire +3 more sources
Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer.
, 2022 The retinoblastoma tumor suppressor (RB) is a critical regulator of E2F-dependent transcription, controlling a multitude of protumorigenic networks including but not limited to cell-cycle control.
Mandigo, AC +13 more
core +1 more source
Developing a pan-cancer research autopsy programme [PDF]
Journal of Clinical Pathology, 2019 AimsRapid procurement of a wide variety of metastatic and primary cancers and normal tissues after death through rapid autopsy opens largely unexplored avenues in cancer research. We describe a high-volume rapid research autopsy programme at a large academic medical centre.MethodsAdvanced-stage cancer patients, most commonly inpatients in palliative ...
Prashant Bavi +7 more
openaire +2 more sources
Prognostic and immunological role of SERPINH1 in pan-cancer
Frontiers in Genetics, 2022 Background: The SERPINH1 gene plays a vital part in tumorigenesis and development, whereas its potential as an immunotherapy target is still unknown. Hence, this research aimed to probe the roles of SERPINH1 in human tumors.Method: Using The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx) database, Oncomine, and SangerBox software, the ...
Huage Zhong +12 more
openaire +3 more sources
Long Noncoding RNA Linc00152 Functions as a Tumor Propellant in Pan-Cancer
Cellular Physiology and Biochemistry, 2017 Background/Aims: The oncogenic role of linc00152 in pan-cancer is unclear. Methods: In this study, RNA-Seq of 33 breast specimens was performed, and the expression of linc00152 was validated by qPCR using 50 paired breast cancer tissues and adjacent ...
Shouping Xu +7 more
doaj +1 more source