Results 61 to 70 of about 3,191,959 (309)
Prognostic implication and immunological value of contactin 1 expression in pan‐cancer
Clinical and Translational Discovery, 2022 Objective Contactin 1 (CNTN1) is associated with developing the cancer progression and nervous system. Although increasing evidence suggests a crucial role for CNTN1 in many research areas, it is still no detailed systematic analysis of CNTN1 and the ...
Lingyun Zhang +4 more
doaj +1 more source
Functional genomics studies of cancer and cells of origin: from pan-cancer to single-cell
, 2020 The development of stratification systems and therapeutical targets is critical for cancer research. Recent advances in high-throughput sequencing enable the gener- ation of a large amount of cancer genomic and transcriptomic data, which can be used to ...
Hu, Zhiyuan
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Lancet Regional Health. Western Pacific, 2022 Summary: Background: Gastric carcinogenesis is a multistep process initiating with chronic gastritis and progressing through atrophy, intestinal metaplasia, and dysplasia to carcinoma.
Dianqin Sun +10 more
doaj +1 more source
National Aboriginal and Torres Strait Islander cancer framework 2015 [PDF]
, 2015 Overview The National Aboriginal and Torres Strait Islander Cancer Framework (the Framework) provides high-level guidance and direction for the many individuals, communities, organisations and governments whose combined efforts are required to address ...
Cancer Australia
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Pan-Cancer Bioinformatics Analysis of Gene UBE2C
Frontiers in Genetics, 2022 Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression.
Lin Yuan +6 more
openaire +3 more sources
Informatics in Medicine Unlocked, 2021 Worldwide, lung cancer is a leading cause of cancer-related deaths and is the most commonly diagnosed form of cancer. A major characteristic of lung cancer is its profound clinical, histological and molecular heterogeneity. This heterogeneity is not only
Zodwa Dlamini +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
ACR Open Rheumatology, 2022 Objective The study objective was to compare incident cancer rates among patients with anti‐neutrophil cytoplasm antibody‐associated vasculitis (AAV) and polyarteritis nodosa (PAN) in Western Australia (WA) with the general population and perform time ...
Joanna Tieu +5 more
doaj +1 more source