Results 171 to 180 of about 3,204,397 (250)

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

open access: yesAdvanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng   +12 more
wiley   +1 more source

Comparative effectiveness of two antimicrobial regimens for the treatment of pan-drug-resistant <i>Acinetobacter baumannii</i> infections: results from the DESPAIR study. [PDF]

open access: yesAntimicrob Agents Chemother
Pontikis K   +20 more
europepmc   +1 more source

Whole genome sequence of pan drug-resistant clinical isolate of Acinetobacter baumannii ST1890. [PDF]

open access: yesPLoS One, 2022
Wongsuk T   +4 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Efficacy of Fosfomycin-Containing Regimens for Treatment of Bacteremia Due to Pan-Drug Resistant Acinetobacter baumannii in Critically Ill Patients: A Case Series Study. [PDF]

open access: yesPathogens, 2023
Assimakopoulos SF   +8 more
europepmc   +1 more source

Bio‐Inspired Oligocellulose‐Regulated Ice‐Water Interfaces Enable Sustained Ion Transport in Frozen Aqueous Zinc Batteries

open access: yesAdvanced Science, EarlyView.
Inspired by antifreeze glycoproteins (AFGPs), we synthesized a type of oligomeric cellulose (OC‐8) to inhibit ice formation and enlarge the inter‐ice water channel for transportation. Typical confocal fluorescence experiments display the expansion of the ice‐water interface for zinc‐ion transport.
Zeyu Zhu   +12 more
wiley   +1 more source

From genomics to treatment: overcoming pan-drug-resistant <i>Klebsiella pneumoniae</i> in clinical settings. [PDF]

open access: yesFront Pharmacol
Pasteran F   +17 more
europepmc   +1 more source

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