Results 141 to 150 of about 837,178 (387)

H+ és HCO3- transzporterek szabályozása humán pancreas ductus sejtekben = Regulation of H+ and HCO3-Transporters in Human Pancreatic Duct Cells [PDF]

open access: yes, 2009
A pancreas nedvben található HCO3- ionok kiválasztásáért a pancreas ductus sejtek felelősek. Jelen pályázatban célul tűztük ki, hogy molekuláris biológiai, transzdukciós és mikrofluorescens technikák felhasználásával megértsük a HCO3- szekréció ...
Rakonczay, Zoltán
core  

Structural similarities and differences between the human and the mouse pancreas

open access: yesIslets, 2015
Mice remain the most studied animal model in pancreas research. Since the findings of this research are typically extrapolated to humans, it is important to understand both similarities and differences between the 2 species.
J. Dolenšek, M. Rupnik, A. Stožer
semanticscholar   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Human pancreas development

open access: yesDevelopment, 2015
A wealth of data and comprehensive reviews exist on pancreas development in mammals, primarily mice, and other vertebrates. By contrast, human pancreatic development has been less comprehensively reviewed.
Rachel E. Jennings   +4 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Wt1 is involved in pancreas development and adult pancreatic homeostasis [PDF]

open access: yes, 2017
The embryonic mesothelium lining the visceral organs gives rise to mesenchymal cells through a localized epithelial-mesenchymal transition (EMT). This has been extensively studied in some cases, such as the heart, where the epicardium gives rise to ...
Aguilera, Beatriz   +4 more
core  

Correction: CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-IRNA-editing

open access: yesMolecular Cancer, 2022
Peng Shen   +13 more
doaj   +1 more source

Pancreas Cancer-Associated Weight Loss. [PDF]

open access: yes, 2019
Unintentional weight loss in patients with pancreatic cancer is highly prevalent and contributes to low therapeutic tolerance, reduced quality of life, and overall mortality.
Denlinger, Crystal S   +7 more
core  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

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